D
David J. Orlicky
Researcher at University of Colorado Denver
Publications - 217
Citations - 7790
David J. Orlicky is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Oxidative stress & Medicine. The author has an hindex of 43, co-authored 186 publications receiving 6467 citations. Previous affiliations of David J. Orlicky include Anschutz Medical Campus & University of Colorado Hospital.
Papers
More filters
Journal ArticleDOI
Correction: Corrigendum: Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome
Miguel A. Lanaspa,Takuji Ishimoto,Nanxing Li,Christina Cicerchi,David J. Orlicky,Philip A. Ruzycki,Christopher J. Rivard,Shinichiro Inaba,Carlos A. Roncal-Jimenez,Elise S. Bales,Christine P. Diggle,Aruna Asipu,J. Mark Petrash,Tomoki Kosugi,Shoichi Maruyama,Laura G. Sánchez-Lozada,James L. McManaman,David T. Bonthron,Yuri Y. Sautin,Richard J. Johnson +19 more
TL;DR: This paper presents a new probabilistic method for estimating the response of the immune system to EMTs to laser-spot assisted, 3D image analysis of EMMARM, which shows clear patterns in the response to laser beams.
Journal ArticleDOI
CD44v6 dependence of premetastatic niche preparation by exosomes.
Thorsten Jung,Donatello Castellana,Pamela Klingbeil,Ines Cuesta Hernández,Mario Vitacolonna,David J. Orlicky,Steve R. Roffler,Pnina Brodt,Margot Zöller +8 more
TL;DR: The metastasizing capacity of the rat pancreatic adenocarcinoma BSp73ASML is strikingly reduced by a knockdown of CD44v4-v7 (ASML(kd), and the role of the CD44 variant isoform (CD44v) in (pre)metastatic niche formation is analyzed.
Journal ArticleDOI
High‐fat and high‐sucrose (western) diet induces steatohepatitis that is dependent on fructokinase
Takuji Ishimoto,Miguel A. Lanaspa,Christopher J. Rivard,Carlos A. Roncal-Jimenez,David J. Orlicky,Christina Cicerchi,Rachel H. McMahan,Manal F. Abdelmalek,Hugo R. Rosen,Matthew R. Jackman,Paul S. MacLean,Christine P. Diggle,Aruna Asipu,Shinichiro Inaba,Tomoki Kosugi,Waichi Sato,Shoichi Maruyama,Laura G. Sánchez-Lozada,Yuri Y. Sautin,James O. Hill,David T. Bonthron,Richard J. Johnson +21 more
TL;DR: The protection in fructokinase knockout mice suggests a key role for fructose (from sucrose) in this development of steatohepatitis, and emphasize the important role of fructose in the development of fatty liver and nonalcoholic steato hepatitis.
Journal ArticleDOI
Expression of survivin in normal, hyperplastic, and neoplastic colonic mucosa
Roberto Gianani,Elke A. Jarboe,David J. Orlicky,Michael Frost,Joanna B. Bobak,Rainer Lehner,Kenneth R. Shroyer +6 more
TL;DR: The expression of survivin is not a specific marker of adenocarcinoma of the colon but does show characteristic and reproducible patterns of expression in non-neoplastic proliferative lesions and in normal colonic mucosa.
Journal ArticleDOI
Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease
James L. McManaman,Elise S. Bales,David J. Orlicky,Matthew R. Jackman,Paul S. MacLean,Shannon Cain,Amanda E. Crunk,Ayla Mansur,Christine E. Graham,Thomas A. Bowman,Andrew S. Greenberg +10 more
TL;DR: This study provides the first evidence that Plin2 contributes to HFD-induced obesity by modulating food intake, and that its absence prevents obesity-associated adipose tissue inflammatory foci and liver steatosis.