L
Lin Mei
Researcher at Case Western Reserve University
Publications - 266
Citations - 18002
Lin Mei is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Neuromuscular junction & Agrin. The author has an hindex of 69, co-authored 245 publications receiving 15903 citations. Previous affiliations of Lin Mei include University of Arizona & Chinese Academy of Sciences.
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Journal ArticleDOI
Linking cortical astrocytic neogenin deficiency to the development of Moyamoya disease-like vasculopathy.
Xiao Ren,Ling-Ling Yao,Jin-Xiu Pan,Jun-Shi Zhang,Lin Mei,Yonggang Wang,Yonggang Wang,Wen Cheng Xiong +7 more
TL;DR: In this paper, the authors provided evidence for cortical astrocytic neogenin (NEO1) deficiency to be a risk factor for the development of moyamoya-like vasculopathy.
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Hepcidin contributes to Swedish mutant APP-induced osteoclastogenesis and trabecular bone loss
Hao-Han Guo,Lei Xiong,Lei Xiong,Jin-Xiu Pan,Jin-Xiu Pan,Daehoon Lee,Kevin Liu,Kevin Liu,Xiao Ren,Bo Wang,Xiao Yang,Shun Cui,Lin Mei,Lin Mei,Lin Mei,Wen Cheng Xiong,Wen Cheng Xiong,Wen Cheng Xiong +17 more
TL;DR: In this paper, the authors used a multiplex antibody array to screen for serum proteins that are altered in Tg2576 mice and identified hepcidin, a master regulator of iron homeostasis.
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The Ig1/2 domain of MuSK binds to muscle surface and is involved in acetylcholine receptor clustering.
TL;DR: Results suggest that the Ig1/2 domain of MuSK is involved in AChR clustering by binding to the muscle surface, and recombinant proteins containing the binding activity can block full-length MuSK binding to muscle cells and agrin-induced AChr clustering.
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Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation.
Sen Lin,Wei Liu,Chun-Lin Chen,Dong Sun,Dong Sun,Jin-Xia Hu,Lei Li,Jian Ye,Lin Mei,Lin Mei,Wen Cheng Xiong,Wen Cheng Xiong +11 more
TL;DR: An unrecognized function of neogen in preventing PHPV pathogenesis is demonstrated, implicating neogenin regulation of neural crest cell delamination/migration and retinal fissure formation as potential underlying mechanisms of PHPV.
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Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast‐Lineage Cells
Bo Wang,Jin-Xiu Pan,Hua-Li Yu,Lei Xiong,Kai Zhao,Shan Xiong,Jun-Peng Guo,Sen Lin,Dong Sun,Lu Zhao,Hao-Han Guo,Lin Mei,Wen Cheng Xiong +12 more
TL;DR: It is shown that mice with Myosin X loss of function, Myo10m/m, exhibit osteoporotic deficits, which are likely due to the increased OC genesis and bone resorption because bone formation is unchanged.