Lin Tang

TL;DR: Novel biocompatible Nir-II aggregation-induced emission dots are facilely assembled and used for NIR-II biomedical fluorescence imaging.

TL;DR: The first D-A type thiopyrylium NIR-II theranostics for synchronous upconversion-mitochondria-targeted cell imaging, in vivo Nir-II osteosarcoma imaging and excellent photothermal efficiency are presented.

TL;DR: Two homologous types of fluorescent probes CH1055‐PEG‐PT and CH10 55‐Peg‐Affibody, which show highly promising results for targeting imaging of osteosarcoma and its lung metastasis, respectively, are designed and synthesized and found to be far superior to that of computed tomography for the early in vivo 143B tumor imaging.

TL;DR: It is the first time that the superior practical applications of this NIR-II probe in dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma imaging and image-guided rat carcinoma surgery were demonstrated.

TL;DR: This report presents the first tumor-homing peptide-based NIR-II probe to diagnose transplantable and spontaneous breast tumors by the active targeting, and exhibited specific Nir-II signals with high spatial and temporal resolution, strong tumor uptake, and remarkable N IR-II image-guided surgery in dimethylbenzanthracene-induced spontaneous breast tumor rats.