L
Lin Yang
Publications - 1
Citations - 594
Lin Yang is an academic researcher. The author has contributed to research in topics: P70-S6 Kinase 1 & Akt/PKB signaling pathway. The author has an hindex of 1, co-authored 1 publications receiving 586 citations.
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An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/− mice
Katrina Podsypanina,Richard T. Lee,Chris Politis,Ian Hennessy,Allison Crane,Janusz Puc,Mehran S. Neshat,Hong Wang,Lin Yang,Jay Gibbons,Phil Frost,Valley C. Dreisbach,John Blenis,Zbigniew Gaciong,Peter E. Fisher,Charles L. Sawyers,Lora Hedrick-Ellenson,Ramon Parsons +17 more
TL;DR: It is shown that transformed cells of PTEN+/− mice have elevated levels of phosphorylated Akt and activated p70/S6 kinase associated with an increase in proliferation and that inhibition of these proteins may be therapeutic for cancer patients with deranged PI3K signaling.