Lina Daniel

TL;DR: This article showed that TCR affinity does not control Th1 effector function acquisition or the functional output of individual effectors following mycobacterial infection in mice, but rather calibrates the rate of cell division to synchronize the distinct processes of T cell proliferation, differentiation, and trafficking.

TL;DR: A distinct yet cooperative role for IL-12 and TCR signalling in Th1 differentiation is revealed and it is suggested that the temporal activation of clones with different TCR affinity is a major strategy to coordinate immune surveillance against persistent pathogens.

TL;DR: The authors showed that mycobacterium tuberculosis infection modifies the structure and function of lymph nodes by increasing the number and paracortical translocation of B cells, which results in the formation of paracental B lymphocyte and CD35+ follicular dendritic cell clusters.

TL;DR: In this article , two laboratory rodent diets, widely used as standard animal feeds and experimental controls, display distinct abilities in supporting mice during influenza infection, showing that diet composition calibrates host survival threshold by regulating adaptive homeostasis and highlights a pivotal role for extrinsic signals in host phenotype and outcome of hostpathogen interaction.

TL;DR: In this paper , the authors show that mycobacterium tuberculosis-infected mice were infected with pulmonary Mycobacteria tuberculosis and showed that naïve lymphocytes are significantly less efficient than non-draining lymph nodes in homing to mediastinal lymph nodes.