Linette R. Klevan

TL;DR: For patients with standard indications for ICD therapy, no indication for cardiac pacing, and an LVEF of 40% or less, dual-chamber pacing offers no clinical advantage over ventricular backup pacing and may be detrimental by increasing the combined end point of death or hospitalization for heart failure.

TL;DR: Atrial pacing may be considered a "safe alternative" when pacing is desired in defibrillator recipients, but affords no clear advantage or disadvantage over a ventricular pacing mode that minimizes pacing altogether.

TL;DR: In this high-risk HF population, patients with reduced baseline eGFR and elevated baseline BNP, lower QRS duration or non- or negative-responders were almost 2-3 fold more likely to have an early adverse outcome (transplant or die at 1 year).