L
Linjing Mu
Researcher at ETH Zurich
Publications - 106
Citations - 2195
Linjing Mu is an academic researcher from ETH Zurich. The author has contributed to research in topics: In vivo & Radioligand. The author has an hindex of 26, co-authored 95 publications receiving 1858 citations. Previous affiliations of Linjing Mu include Nankai University & Paul Scherrer Institute.
Papers
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Journal ArticleDOI
Synthesis, 18F-labeling, and in vitro and in vivo studies of bombesin peptides modified with silicon-based building blocks.
Aileen Höhne,Linjing Mu,Michael Honer,P. August Schubiger,Simon M. Ametamey,Keith Graham,Timo Stellfeld,Sandra Borkowski,Dietmar Berndorff,Ulrich Klar,Ulrike Voigtmann,John E. Cyr,Matthias Friebe,Ludger Dinkelborg,Ananth Srinivasan +14 more
TL;DR: This study demonstrates the applicability of the silicon-based one-step n.c. radiolabeling method for the synthesis of new 18F-labeled bombesin derivatives for the PET imaging of GRPr expression in prostate tumor.
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Silicon‐Based Building Blocks for One‐Step 18F‐Radiolabeling of Peptides for PET Imaging
Linjing Mu,Aileen Höhne,P. August Schubiger,Simon M. Ametamey,Keith Graham,John E. Cyr,Ludger Dinkelborg,Timo Stellfeld,Ananth Srinivasan,Ulrike Voigtmann,Ulrich Klar +10 more
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Energetics of Multistep versus One-step Hydride Transfer Reactions of Reduced Nicotinamide Adenine Dinucleotide (NADH) Models with Organic Cations and p-Quinones.
TL;DR: Practical guidelines suggest that a mutistep mechanism would be followed if the energy gap of the initial electron transfer between the NADH model compound and the reducing substrate is considerably smaller than the empirical critical limit of 1.0 V for an endothermic e(-)(T).
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Direct One-Step18F-Labeling of Peptides via Nucleophilic Aromatic Substitution
Becaud Jessica,Linjing Mu,Mylène Karramkam,P. A. Schubiger,Simon M. Ametamey,Keith Graham,Timo Stellfeld,Lutz Lehmann,Sandra Borkowski,Dietmar Berndorff,Ludger Dinkelborg,Ananth Srinivasan,René Smits,Beate Koksch +13 more
TL;DR: The results of the one-step [18F]-fluorination of tetrapeptides and bombesin peptides show that the direct 18F-labeling of peptides is feasible under mild conditions and in good radiochemical yields.
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18F-Radiolabeling of Aromatic Compounds Using Triarylsulfonium Salts
Linjing Mu,Cindy R. Fischer,Jason P. Holland,Becaud Jessica,P. August Schubiger,Roger Schibli,Simon M. Ametamey,Keith Graham,Timo Stellfeld,Ludger Dinkelborg,Lutz Lehmann +10 more
TL;DR: A new method for the 18F-radiolabeling of aromatic compounds based on the aromatic nucleophilic substitution (SNAr) reaction using triarylsulfonium salts has been developed and indicates that sulfonium ions have the potential to be optimized for labeling nonactivated and deactivated aryl rings that have Hammett σP substituent constants greater than –0.170.