L
Liu-Zhu Gong
Researcher at University of Science and Technology of China
Publications - 61
Citations - 3508
Liu-Zhu Gong is an academic researcher from University of Science and Technology of China. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 29, co-authored 61 publications receiving 3340 citations. Previous affiliations of Liu-Zhu Gong include Chinese Academy of Sciences & Nankai University.
Papers
More filters
Journal ArticleDOI
Highly Diastereo- and Enantioselective Direct Aldol Reactions of Cycloketones with Aldehydes Catalyzed by a trans-4-tert-Butyldimethylsiloxy-L-proline Amide.
TL;DR: In this article, an organocatalyst derived from trans-4-hydroxy- l -proline and (1S,2S)-1,2-diphenyl-2-aminoethanol catalyzes the direct aldol reactions of cycloketones with a wide scope of aldehydes in high yields and with excellent diastereoselectivities of up to >99:1 and enanti-lectivities up to 99% ee.
Journal ArticleDOI
Palladium‐Catalyzed Allylic Alkylation of tert‐Butyl(diphenylmethylene)‐glycinate with Simple Allyl Esters under Chiral Phase Transfer Conditions.
Guoshu Chen,Yijian Deng,Liu-Zhu Gong,Aiqiao Mi,Xin Cui,Yaozhong Jiang,Michael C. K. Choi,Albert S. C. Chan +7 more
TL;DR: The first example of palladium-catalyzed allylic alkylation of an imino ester with simple allyl esters in the presence of a chiral quaternary ammonium salt is reported in this paper.
Journal ArticleDOI
Organo-Catalyzed Highly Diastereo- and Enantio-Selective Direct Aldol Reactions in Water.
TL;DR: In this paper, the asymmetric direct aldol reactions of a wide scope of aromatic aldehydes, with unmodified ketones in the presence of 1 ǫ% of organocatalyst prepared from (2 R, 3 R )-diethyl 2-amino-3-hydroxysuccinate and trans -4-hydroxy- l -proline, were performed in water.
Journal ArticleDOI
The First Use of Chiral Oxazoline Ligands in the Highly Enantioselective Diethylzinc Addition to Diphenylphosphinoyl Imines.
Xiaomei Zhang,Wenqing Lin,Liu-Zhu Gong,Aiqiao Mi,Xin Cui,Yaozhong Jiang,Michael C. K. Choi,Albert S. C. Chan +7 more
TL;DR: A series of chiral oxazolines, which had been conveniently prepared from commercially available (1S,2S)-2-amino-1-phenylpropane-1,3-diol, was applied in the diethylzinc addition to diphenylphosphinoyl imines to give high yields of 68-84% and excellent e.g. values of 90-93% as mentioned in this paper.
Journal ArticleDOI
Asymmetric Direct Aldol Reaction Catalyzed by an L-Prolinamide Derivative: Considerable Improvement of the Catalytic Efficiency in the Ionic Liquid.
TL;DR: In this article, the asymmetric direct aldol reactions of a wide scope of aldehydes with unmodified ketones in the presence of 20 mol% increase in the number of modifications was performed in ionic liquids.