Long Li

TL;DR: Baicalin may attenuate renal ischemia-reperfusion injury by inhibiting proinflammatory responses and mitochondria-mediated apoptosis and these effects are associated with the TLR2/4 signaling pathway and mitochondrial stress.

TL;DR: RSV inhibited inflammatory responses and improved renal function after renal IRI and exerts its greatest effects by blocking inflammatory responses, lowering oxidative stress, and reducing apoptosis via the Nrf2/TLR4/NF-κB pathway.

TL;DR: Renal TCs protect against renal IRI via an inflammation‐independent pathway and that growth factors play a significant role in this mechanism, and may protect TECs in certain microenvironments while interacting with other cells.

TL;DR: Thioether-cyclized helix B peptide was significantly stable in vivo and in vitro, and the phosphorylation of autophagy protein mTORC1 was dramatically reduced upon CHBP treatment, indicating that the novel metabolically stable CHBP is a promising therapeutic medicine for kidney IR injury treatment.

TL;DR: It is revealed that Baicalin pretreatment serves a protective role against H2O2-induced cytotoxicity in HK-2 cells, where the inhibition of ER stress and the activation of downstream Nrf2 signaling are involved.