L
Lorella Vecchio
Researcher at Qassim University
Publications - 32
Citations - 1082
Lorella Vecchio is an academic researcher from Qassim University. The author has contributed to research in topics: Stromal cell & Tumor microenvironment. The author has an hindex of 16, co-authored 29 publications receiving 942 citations. Previous affiliations of Lorella Vecchio include University of Pavia & University of Ngaoundéré.
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Journal ArticleDOI
Insulin resistance and cancer: the role of insulin and IGFs
Sefirin Djiogue,Armel Herve Nwabo Kamdje,Lorella Vecchio,Maulilio John Kipanyula,Mohammed Farahna,Yousef H. Aldebasi,Paul F. Seke Etet +6 more
TL;DR: Evidence highlighting recent advances in understanding on the role of ILPs as the link between insulin resistance and cancer and between immune deregulation and cancer in obesity are discussed, as well as those areas where there remains a paucity of data.
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Signaling pathways bridging microbial-triggered inflammation and cancer
Maulilio John Kipanyula,Paul F. Seke Etet,Lorella Vecchio,Mohammed Farahna,Elias Nchiwan Nukenine,Armel Herve Nwabo Kamdje,Armel Herve Nwabo Kamdje +6 more
TL;DR: Recent findings on the implication of inflammatory signaling pathways in microbial-triggered carcinogenesis as well as the possible role of microbiota modulation in cancer prevention are herein summarized and discussed.
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Signaling pathways in breast cancer: therapeutic targeting of the microenvironment.
Armel Herve Nwabo Kamdje,Paul F. Seke Etet,Lorella Vecchio,Jean-Marc Muller,Mauro Krampera,Kiven Erique Lukong +5 more
TL;DR: The tumor microenvironment is now recognized as a significant factor in cancer treatment response and the therapeutic targeting of the microenvironment in breast cancer is also considered.
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Ultrastructural analysis of testes from mice fed on genetically modified soybean.
TL;DR: The results point out that the immunolabelling for Sm antigen, hnRNPs, SC35 and RNA Polymerase II is decreased in 2 and 5 month-old GM-fed mice, and is restored to normal at 8 months, and the number of perichromatin granules is higher and the nuclear pore density lower.
Journal ArticleDOI
Developmental pathways associated with cancer metastasis: Notch, Wnt, and Hedgehog.
Armel Herve Nwabo Kamdje,Paul Takam Kamga,Richard Tagne Simo,Lorella Vecchio,Paul F. Seke Etet,Jean-Marc Muller,Giulio Bassi,Erique Lukong,Raghuveera Kumar Goel,Jérémie Mbo Amvene,Mauro Krampera +10 more
TL;DR: Experimental data suggesting pivotal roles for developmental pathways in cancer development and metastasis are summarized and discussed, and targeted antimetastatic therapies based on Notch, Wnt, and Hedgehog pathways are discussed.