Loris De Cecco

TL;DR: Gene expression profiling of a subset of 31 tumors performed using cDNA microarray chips showed no strong differences in global gene expression among the different cases, however, a supervised analysis of the obtained data identified a portion of genes differentially expressed in tumors carrying BRAF mutation or RTK rearrangement.

TL;DR: A cross-evaluation of miRNA expression in mesothelioma and human mesothelial cells is reported, for the first time, and the reduced expression of two miRNAs correlated with better survival of patients with sarcomatoid subtype.

TL;DR: Estimates of classification accuracies applied to two independent microarray datasets highlighted the poor performance of treatment-response predictive models that can be achieved with the sample sizes of patients and informative genes to date.

TL;DR: A robust molecularly defined subtype classification in HNSCC is reported that can improve patient selection and pave the way to the development of appropriate therapeutic strategies.

TL;DR: MiR-506 is a robust clinical marker for chemotherapy response and survival in serous ovarian cancers and has important therapeutic value in sensitizing cancer cells to chemotherapy.