L
Lorraine A. Chantrill
Researcher at Wollongong Hospital
Publications - 67
Citations - 10491
Lorraine A. Chantrill is an academic researcher from Wollongong Hospital. The author has contributed to research in topics: Pancreatic cancer & Cancer. The author has an hindex of 22, co-authored 51 publications receiving 7940 citations. Previous affiliations of Lorraine A. Chantrill include Garvan Institute of Medical Research & University of New South Wales.
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Journal ArticleDOI
The Management of Unresectable, Advanced Gastrointestinal Stromal Tumours
Tiffany Foo,David Goldstein,Eva Segelov,Jeremy Shapiro,Nick Pavlakis,Jayesh Desai,Desmond Yip,John Zalcberg,Timothy J. Price,Adnan Nagrial,Lorraine A. Chantrill,M. Burge,Christos S. Karapetis,Niall C. Tebbutt,Amitesh Roy +14 more
TL;DR: The authors in this article provide an overview of the key trials that have changed clinical practice, discuss the molecular drivers of GISTs, the importance of molecular testing and directing therapy according to molecular targets, as well as future strategies in the management of advanced GIST.
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Survival benefit of second-line chemotherapy in advanced pancreatic adenocarcinoma: A systematic review of the literature.
TL;DR: The aim of this analysis was to compare the different therapeutic approaches in this setting, and the rate of second line treatment delivery and its influence on reported overall survival.
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Metastatic pancreatic ductal adenocarcinoma: diagnosis and treatment with a view to the future.
Adrian M J Pokorny,Venessa T. Chin,Adnan Nagrial,Desmond Yip,Desmond Yip,Lorraine A. Chantrill +5 more
TL;DR: The evidence behind the currently used regimens and the potential future of pancreatic cancer care are discussed, while the potential of targeted therapies or immunotherapies are introduced.
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Targeting the Rho-ROCK pathway to treat pancreatic cancer: The use of unique preclinical models to ascertain the effects on cancer growth and metastasis.
Venessa T. Chin,James R.W. Conway,Adnan Nagrial,Lorraine A. Chantrill,Angela Chou,Angela Steinmann,Anthony J. Gill,Mark Pinese,Jiamin Wu,Amber L. Johns,Alison Dury,Andrew V. Biankin,Paul Timpson,Marina Pajic +13 more
TL;DR: The aim was to analyse the effects of inhibiting ROCK-1 using specific small molecule inhibitors (Fasudil and Y-27632) in well annotated and robust pre-clinical model systems generated as part of the APGI efforts.
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Safety and efficacy of bevacizumab and systemic therapy in metastatic colorectal cancer (mCRC) patients with peritoneal disease in the Treatment of Recurrent and Advanced Colorectal Cancer (TRACC) database.
Aflah Roohullah,Hui-Li Wong,Katrin Marie Sjoquist,Kathryn M. Field,Ben Tran,Jeremy Shapiro,Joseph McKendrick,Desmond Yip,Louise M. Nott,Peter Gibbs,Lorraine A. Chantrill +10 more
TL;DR: TRACC is a prospective, multisite, mCRC registry with data collection ongoing at 14 Australian hospitals since July 2009, and patients with peritoneal metastases from CRC are considered a poor prognostic group.