Louise A. Koopman

TL;DR: Natural killer cells constitute 50–90% of lymphocytes in human uterine decidua in early pregnancy and are compared with the CD56bright and CD56dim peripheral NK cell subsets by microarray analysis, with verification of results by flow cytometry and RT-PCR.

TL;DR: Findings indicate that epithelial differentiation and tumor cell viability are associated, and that EMT regulators in "K-Ras-addicted" cancers represent candidate therapeutic targets.

TL;DR: During pregnancy the uterine decidua is populated by large numbers of natural killer cells with a phenotype CD56superbrightCD16−CD9+KIR+ distinct from both subsets of peripheral blood NK cells, and these progenitors produced NK cells when cultured in conditioned medium from decidual stromal cells supplemented with IL-15 and stem cell factor.

TL;DR: It is reported that WAS patients have increased percentages of peripheral blood NK cells and that fresh enriched NK cells from two patients with a WASp mutation have defective cytolytic function.

TL;DR: These NK cell–specific evasion mechanisms fall into distinct mechanistic categories used in numerous virus families, including means of escaping detection by both the innate and adaptive immune responses.