L
Luc Brunsveld
Researcher at Eindhoven University of Technology
Publications - 220
Citations - 11024
Luc Brunsveld is an academic researcher from Eindhoven University of Technology. The author has contributed to research in topics: Supramolecular chemistry & Chemistry. The author has an hindex of 49, co-authored 200 publications receiving 9528 citations. Previous affiliations of Luc Brunsveld include DSM & Max Planck Society.
Papers
More filters
Journal ArticleDOI
Reversible Polymers Formed from Self-Complementary Monomers Using Quadruple Hydrogen Bonding
Rint P. Sijbesma,Felix Hugo Beijer,Felix Hugo Beijer,Luc Brunsveld,Luc Brunsveld,B. J. B. Folmer,B. J. B. Folmer,J. H. K. Ky Hirschberg,J. H. K. Ky Hirschberg,Ronald Frans Maria Lange,Ronald Frans Maria Lange,Jimmy K. L. Lowe,Jimmy K. L. Lowe,E. W. Meijer,E. W. Meijer +14 more
TL;DR: 2-ureido-4-pyrimidone that dimerize strongly in a self-complementary array of four cooperative hydrogen bonds were used as the associating end group in reversible self-assembling polymer systems.
Journal ArticleDOI
Helical self-assembled polymers from cooperative stacking of hydrogen-bonded pairs
J.H.K.K. Hirschberg,Luc Brunsveld,A. Ramzi,Jef A. J. M. Vekemans,Rint P. Sijbesma,E. W. Meijer +5 more
TL;DR: This work describes a general strategy for the design of functionalized monomer units and their association in either water or alkanes into non-covalently linked polymeric structures with controlled helicity and chain length.
Journal ArticleDOI
Modulators of Protein-Protein Interactions
TL;DR: This research presents a novel and scalable approaches called “Smart Gene Regulation” that allows for real-time annotation of the FISH signal in the Eindhoven–Borff–Seiden cellular automaton.
Journal ArticleDOI
Small-molecule inhibition of APT1 affects Ras localization and signaling
Frank J. Dekker,Oliver Rocks,Nachiket Vartak,Sascha Menninger,Christian Hedberg,Rengarajan Balamurugan,Stefan Wetzel,Steffen Renner,Marc Gerauer,Beate Schölermann,Marion Rusch,John W. Kramer,Daniel Rauh,Geoffrey W. Coates,Luc Brunsveld,Philippe I. H. Bastiaens,Herbert Waldmann +16 more
TL;DR: This work presents the knowledge-based development and characterization of a potent inhibitor of acyl protein thioesterase 1 (APT1), a bona fide depalmitoylating enzyme that is, so far, poorly characterized in cells.
Journal ArticleDOI
Combining supramolecular chemistry with biology
TL;DR: This tutorial review focuses on the possibilities of the marriage of synthetic supramolecular architectures and biological systems, and highlights that synthetic supramsolecular elements are for example ideal platforms for the recognition and modulation of proteins and cells.