L
Luca Vanella
Researcher at University of Catania
Publications - 152
Citations - 4782
Luca Vanella is an academic researcher from University of Catania. The author has contributed to research in topics: Heme oxygenase & Adiponectin. The author has an hindex of 38, co-authored 137 publications receiving 4058 citations. Previous affiliations of Luca Vanella include University of Brescia & New York Medical College.
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Journal ArticleDOI
Tissue Transglutaminase Expression During Neural Differentiation of Human Mesenchymal Stem Cells
Luca Vanella,Giuseppina Raciti,Ignazio Barbagallo,Roberta Bonfanti,Nader G. Abraham,Agata Campisi +5 more
TL;DR: The presence of multiple TGs in hMSCs during neural differentiation in vitro induced by GFs is demonstrated, and it is suggested that TG2 may be part of the downstream events associated to neural differentiation.
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Oxidized HDL and Isoprostane Exert a Potent Adipogenic Effect on Stem Cells: Where in the Lineage?
Stephen J. Peterson,Luca Vanella,Angelica Bialczak,Joseph Schragenheim,Ming Li,Lars Bellner,Joseph I. Shapiro,Nader G. Abraham,Nader G. Abraham +8 more
TL;DR: The development of adipocytes in mice and humans follows a well-defined pathway that commences with a common pluripotent mesenchymal stem cell (MSC), ie.
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Non-competitive heme oxygenase-1 activity inhibitor reduces non-small cell lung cancer glutathione content and regulates cell proliferation
Mariarita Spampinato,Giuseppe Sferrazzo,Valeria Pittalà,Michelino Di Rosa,Luca Vanella,Loredana Salerno,Valeria Sorrenti,Giuseppe Carota,Nunziatina Laura Parrinello,Marco Raffaele,Daniele Tibullo,Giovanni Li Volti,Ignazio Barbagallo +12 more
TL;DR: Results show that selective HO-1 inhibition significantly impairs NSCLC progression and may represent a possible pharmacological strategy for new chemotherapy agents.
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Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation.
Loredana Salerno,Luca Vanella,Valeria Sorrenti,Valeria Consoli,Valeria Ciaffaglione,Antonino N. Fallica,Vittorio Canale,Paweł Zajdel,Rosario Pignatello,Sebastiano Intagliata +9 more
TL;DR: In this article, the first mutual prodrug of 5-fluorouracil and heme oxygenase1 inhibitor (5-FU/HO-1 hybrid) has been designed, synthesised, and evaluated for its in vitro chemical and enzymatic hydrolysis stability.
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Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity.
Antonino N. Fallica,Valeria Sorrenti,Agata Grazia D’Amico,Loredana Salerno,Giuseppe Romeo,Sebastiano Intagliata,Valeria Consoli,Giuseppe Floresta,Antonio Rescifina,Velia D'Agata,Luca Vanella,Valeria Pittalà +11 more
TL;DR: In this paper, an amide linker in the central spacer and an imidazole were fixed, and the hydrophobic moiety required by the pharmacophore was largely modified.