L
Luca Vanella
Researcher at University of Catania
Publications - 152
Citations - 4782
Luca Vanella is an academic researcher from University of Catania. The author has contributed to research in topics: Heme oxygenase & Adiponectin. The author has an hindex of 38, co-authored 137 publications receiving 4058 citations. Previous affiliations of Luca Vanella include University of Brescia & New York Medical College.
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Journal ArticleDOI
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.
Valeria Sorrenti,Valeria Pittalà,Giuseppe Romeo,Emanuele Amata,Maria Dichiara,Agostino Marrazzo,Rita Turnaturi,Orazio Prezzavento,Ignazio Barbagallo,Luca Vanella,Antonio Rescifina,Giuseppe Floresta,Daniele Tibullo,Francesco Di Raimondo,Sebastiano Intagliata,Loredana Salerno +15 more
TL;DR: It is found that many hybrids were able to inhibit the enzymatic activity of both targets and to reduce the viability of CML-IM resistant cells, showing that a single molecular entity may reduce the resistance phenomenon.
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Successful modulation of type 2 diabetes in db/db mice with intra-bone marrow--bone marrow transplantation plus concurrent thymic transplantation.
Ming Li,Nader G. Abraham,Luca Vanella,Yuming Zhang,Muneo Inaba,Naoki Hosaka,Sho Ichi Hoshino,Ming Shi,Yoko M. Ambrosini,M. Eric Gershwin,Susumu Ikehara +10 more
TL;DR: The data show that IBM-BMT + TT treatment normalizes T cell subsets, cytokine imbalance and insulin sensitivity in the db/db mouse, suggesting that IBM +-TT is a viable therapeutic option in the treatment of T2 DM.
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Effect of a Natural Supplement Containing Curcuma Longa, Guggul, and Chlorogenic Acid in Patients With Metabolic Syndrome
Angelo Maria Patti,Khalid Al-Rasadi,Niki Katsiki,Yajnavalka Banerjee,Dragana Nikolic,Luca Vanella,Rosaria Vincenza Giglio,Valeria Ausilia Giannone,Giuseppe Montalto,Manfredi Rizzo +9 more
TL;DR: After few months of treatment Kepar seems to exert beneficial effects in patients with metabolic syndrome, and no significant changes were found in the other appraised parameters, including oxidative stress.
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Silibinin Regulates Lipid Metabolism and Differentiation in Functional Human Adipocytes.
Ignazio Barbagallo,Luca Vanella,Maria Teresa Cambria,Daniele Tibullo,Justyna Godos,Laura Guarnaccia,Agata Zappalà,Fabio Galvano,Giovanni Li Volti +8 more
TL;DR: The findings suggest that silibinin increases UCPs expression by stimulation of SIRT1, PPARα, and Pgc-1α, improved metabolic parameters, decreased lipid mass leading to the formation of functional adipocytes.
Journal ArticleDOI
Novel sigma receptor ligands: synthesis and biological profile.
Orazio Prezzavento,Agata Campisi,S Ronsisvalle,Giovanni Li Volti,Agostino Marrazzo,Vincenzo Bramanti,Giuseppe Cannavò,Luca Vanella,Alfredo Cagnotto,Tiziana Mennini,Riccardo Ientile,Giuseppe Ronsisvalle +11 more
TL;DR: It is suggested that 4b may act as a sigma1/sigma2 agonist and that the sigma ligands may modulate TG-2 differently.