L
Lucas Liaudet
Researcher at University of Lausanne
Publications - 239
Citations - 19292
Lucas Liaudet is an academic researcher from University of Lausanne. The author has contributed to research in topics: Poly ADP ribose polymerase & Inflammation. The author has an hindex of 67, co-authored 220 publications receiving 17339 citations. Previous affiliations of Lucas Liaudet include University Hospital of Lausanne & Boston Children's Hospital.
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Nitric Oxide and Peroxynitrite in Health and Disease
TL;DR: Current evidence indicates that most of the cytotoxicity attributed to NO is rather due to peroxynitrite, produced from the diffusion-controlled reaction between NO and another free radical, the superoxide anion, which is presented in detail in this review.
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Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation.
Francisco Garcia Soriano,László Virág,Prakash Jagtap,Éva Szabó,Jon G. Mabley,Lucas Liaudet,Anita Marton,Dale G. Hoyt,Kanneganti G.K. Murthy,Andrew L. Salzman,Garry J. Southan,Csaba Szabó +11 more
TL;DR: In this article, the authors reported that activation of poly(ADP-ribose) polymerase (PARP) is an important factor in the pathogenesis of endothelial dysfunction in diabetes.
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The role of oxidative stress during inflammatory processes
TL;DR: This article reviews in detail the current knowledge on the fundamental connections between oxidative stress and inflammatory processes, with a special emphasis on the danger molecule high-mobility group box-1, the TLRs, the NLRP-3 receptor, and the inflammasome, as well as the transcription factor nuclear factor-κB.
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Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy
Mohanraj Rajesh,Partha Mukhopadhyay,Sandor Batkai,Vivek Patel,Keita Saito,Shingo Matsumoto,Yoshihiro Kashiwaya,Béla Horváth,Bani Mukhopadhyay,Lauren Becker,György Haskó,Lucas Liaudet,David A. Wink,Aristidis Veves,Raphael Mechoulam,Pal Pacher +15 more
TL;DR: It is suggested that cannabidiol may have great therapeutic potential in the treatment of diabetic complications, and perhaps other cardiovascular disorders, by attenuating oxidative/nitrative stress, inflammation, cell death and fibrosis.
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Drug-induced mitochondrial dysfunction and cardiotoxicity.
TL;DR: The mechanisms of mitochondrion-mediated cardiotoxicity of commonly used drugs and some potential cardioprotective strategies to prevent these toxicities are discussed.