Lucas Michel-Todó

TL;DR: A system for controlled sexual conversion in the human malaria parasite Plasmodium falciparum, based on conditional expression of the PfAP2-G transcription factor is described, enabling the characterization of committed and early sexual stages without further purification.

TL;DR: A set of epitopes that have <70% identity to human or human microbiome protein sequences and represent the basis toward the development of an epitope-based vaccine against T. cruzi are prioritized by means of a computer-aided strategy.

TL;DR: In this article, the authors showed that PfAP2-HS, a transcription factor in the ApiAP2 family, regulates the protective heat-shock response in Plasmodium falciparum.

TL;DR: In this paper, the authors proposed a vaccine strategy based on multiple epitopes from multiple antigens to counteract the parasites' biological complexity, which can represent a major breakthrough towards the management and control of the disease.

TL;DR: In this paper, the authors provided a detailed characterization of the complete P. falciparum transcriptome across the full intraerythrocytic development cycle (IDC) at the onset of a blood infection in malaria-naive human volunteers.