L
Lucia Casadei
Researcher at Ohio State University
Publications - 35
Citations - 1307
Lucia Casadei is an academic researcher from Ohio State University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 15, co-authored 28 publications receiving 1029 citations. Previous affiliations of Lucia Casadei include University of Urbino & The Ohio State University Wexner Medical Center.
Papers
More filters
Journal ArticleDOI
C2C12 myoblasts release micro-vesicles containing mtDNA and proteins involved in signal transduction
Michele Guescini,Diego Guidolin,Luciana Vallorani,Lucia Casadei,Anna Maria Gioacchini,Pasquale Tibollo,Michela Battistelli,Elisabetta Falcieri,L. Battistin,L. F. Agnati,Vilberto Stocchi +10 more
TL;DR: The present findings demonstrate that skeletal muscle cells release micro-vesicles, which probably have an important role in the communication processes within skeletal muscles and between skeletal muscle and other organs and suggest possible new diagnostic approaches to skeletal muscle diseases.
Journal ArticleDOI
Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation
Pierluigi Gasparini,Francesca Lovat,Matteo Fassan,Lucia Casadei,Luciano Cascione,Naduparambil K. Jacob,Stefania Carasi,Dario Palmieri,Stefan Costinean,Charles L. Shapiro,Kay Huebner,Carlo M. Croce +11 more
TL;DR: Overexpression of microRNA 155 in human breast cancer cells reduces the levels of RAD51 and affects the cellular response to IR, indicating that miR-155 regulates DNA repair activity and sensitivity to IR by repressing RAD51 in breast cancer.
Journal ArticleDOI
Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression.
Lucia Casadei,Lucia Casadei,Federica Calore,Chad J. Creighton,Michele Guescini,Kara Batte,Kara Batte,O. Hans Iwenofu,Abeba Zewdu,Abeba Zewdu,Danielle Braggio,Danielle Braggio,Kate Lynn J. Bill,Kate Lynn J. Bill,Paolo Fadda,Francesca Lovat,Gonzalo Lopez,Gonzalo Lopez,Pierluigi Gasparini,James L. Chen,James L. Chen,Raleigh D. Kladney,Raleigh D. Kladney,Gustavo Leone,Gustavo Leone,Dina Lev,Carlo M. Croce,Raphael E. Pollock,Raphael E. Pollock +28 more
TL;DR: The possibility that the pattern of circulating miRNAs may identify recurrence prior to radiological detectability is established, establishing the possibility that insight into disease outcome and as a possible approach to monitor treatment efficacy is provided.
Journal ArticleDOI
Biochemical characterisation and antioxidant activity of mycelium of Ganoderma lucidum from Central Italy
Roberta Saltarelli,Paola Ceccaroli,Mirco Iotti,Alessandra Zambonelli,Michele Buffalini,Lucia Casadei,Luciana Vallorani,Vilberto Stocchi +7 more
TL;DR: Ganoderma lucidum species is currently popular and used in the formulation of nutraceuticals and as functional foods, but a broad biochemical characterisation of its mycelium has not yet been reported.
Journal ArticleDOI
SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma
Kate Lynn J. Bill,Jeannine Garnett,Isabelle Meaux,Xiao Yen Ma,Chad J. Creighton,Svetlana Bolshakov,Cedric Barriere,Laurent Debussche,Alexander J. Lazar,Bethany C. Prudner,Lucia Casadei,Danielle Braggio,Gonzalo Lopez,Abbie Zewdu,Hemant K. Bid,Dina Lev,Raphael E. Pollock,Raphael E. Pollock +17 more
TL;DR: In vitro and in vivo results support its use as a potential therapeutic strategy for the treatment of DDLPS, and SAR405838 is currently in early-phase clinical trials for a number of malignancies, including sarcoma.