L
Luciana Relly Bertolini
Researcher at Pontifícia Universidade Católica do Rio Grande do Sul
Publications - 49
Citations - 842
Luciana Relly Bertolini is an academic researcher from Pontifícia Universidade Católica do Rio Grande do Sul. The author has contributed to research in topics: Oocyte & Somatic cell nuclear transfer. The author has an hindex of 13, co-authored 49 publications receiving 760 citations. Previous affiliations of Luciana Relly Bertolini include University of Rio Grande & University of Fortaleza.
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Journal ArticleDOI
Increased Gene Targeting in Ku70 and Xrcc4 Transiently Deficient Human Somatic Cells
TL;DR: It is demonstrated that the transient knockdown of integral NHEJ proteins, Ku70 and Xrcc4, by RNAi in human HCT116 cells has a remarkable effect on gene targeting/random insertions ratios and is a viable approach to increase the frequency of gene targeting events.
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Milk with and without lactoferrin can influence intestinal damage in a pig model of malnutrition.
Lydia C Garas,Cristiano Feltrin,M. Kristina Hamilton,Jill V. Hagey,James D. Murray,Luciana Relly Bertolini,Marcelo Bertolini,Helen E. Raybould,Elizabeth A. Maga +8 more
TL;DR: This pig model of malnutrition mimics salient aspects of the human condition and demonstrates that cow milk can stimulate the repair of damage to the intestinal epithelium caused by protein and calorie restriction with hLF milk improving this recovery to a greater extent.
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Etiology and severity of diarrheal diseases in infants at the semiarid region of Brazil: A case-control study
Aldo A. M. Lima,Domingos B. Oliveira,Josiane da Silva Quetz,Alexandre Havt,Mara M. G. Prata,Ila F. N. Lima,Alberto M. Soares,José Q. Filho,Noélia L. Lima,Pedro H. Q. S. Medeiros,Ana K. S. Santos,Herlice N. Veras,Rafhaella N D G Gondim,Rafaela C. Pankov,Mariana D. Bona,Francisco Adelvane de Paulo Rodrigues,Renato de Azevedo Moreira,Ana Cristina de Oliveira Monteiro Moreira,Marcelo Bertolini,Luciana Relly Bertolini,Vicente José de Figueirêdo Freitas,Eric R. Houpt,Richard L. Guerrant,Richard L. Guerrant +23 more
TL;DR: Six enteropathogens: Norov virus, Adenovirus, Rotavirus, STEC, Giardia spp.
Journal ArticleDOI
Transient depletion of Ku70 and Xrcc4 by RNAi as a means to manipulate the non-homologous end-joining pathway
Luciana Relly Bertolini,Marcelo Bertolini,Gary B. Anderson,Elizabeth A. Maga,Knut R. Madden,James D. Murray +5 more
TL;DR: The results highlight the possibility of a successful means to manipulate the NHEJ pathway by RNAi and down-regulation of Ku70 and Xrcc4 resulted in a concomitant depletion of bothKu70 and Ku86 proteins.
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Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apolipoprotein E-deficient mice
Celina V. Araújo,Cicera R. Lazzarotto,Cristhyane Costa de Aquino,Ítalo L Figueiredo,Tiê Bezerra Costa,L.A. de Oliveira Alves,Ronaldo A. Ribeiro,Luciana Relly Bertolini,A.A.M. Lima,Gerly Anne de Castro Brito,Reinaldo B. Oriá +10 more
TL;DR: Findings suggest APOE-independent Ala-Gln regenerative effects after 5-FU challenge, and suggest apoE deficiency reduces the healing effect of alanyl-glutamine treatment, a recognized gut-trophic nutrient, during tissue recovery after5-FU-induced intestinal mucositis.