Luciano Vittozzi

TL;DR: The data indicated that CYP1A2 and 2B6 are suggested as possible metabolic biomarkers of susceptibility to OPT toxic effect at the actual human exposure levels, while the role of CYP3A4 is more significant to the low-affinity component of OPT bioactivation.

TL;DR: In many European countries neonatal screening has been introduced over the last 50 years as an important public health programme, depending on health care structure, available funds, local politics, input from professional groups, parent groups, and the general public this introduction has led to different approaches in the way the screenings have been set up, financed and governed.

TL;DR: Fathead minnow was the most resistant species in practically all the available comparisons and no dependence of the selective toxicity on the n-octanol/water partition coefficient of the chemicals could be observed.

TL;DR: The results indicate that the metabolism plays a key role in the bioaccumulation and in the species specific toxicity of diazinon in fish.

TL;DR: This survey gives a first comprehensive overview of the steps following a positive screening result in European NBS programmes, revealing substantial variation of national screening panels, but also a lot of similarities.