L
Lucie I. Bruijn
Publications - 1
Citations - 1401
Lucie I. Bruijn is an academic researcher. The author has contributed to research in topics: Metabotropic glutamate receptor 2 & SLC1A2. The author has an hindex of 1, co-authored 1 publications receiving 1324 citations.
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β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
Jeffrey D. Rothstein,Sarjubhai Patel,Melissa R. Regan,Christine Haenggeli,Yanhua H. Huang,Dwight E. Bergles,Lin Jin,Margaret Dykes Hoberg,Svetlana Vidensky,Dorothy S. Chung,Shuy Vang Toan,Lucie I. Bruijn,Zao-Zhong Su,Pankaj Gupta,Paul B. Fisher +14 more
TL;DR: Using a blinded screen of 1,040 FDA-approved drugs and nutritionals, it is discovered that many β-lactam antibiotics are potent stimulators of GLT1 expression, and this action appears to be mediated through increased transcription of theGLT1 gene.