L
Luciene Covolan
Researcher at Federal University of São Paulo
Publications - 64
Citations - 1830
Luciene Covolan is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Epilepsy & Hippocampal formation. The author has an hindex of 23, co-authored 60 publications receiving 1573 citations. Previous affiliations of Luciene Covolan include University of Oslo & University of São Paulo.
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Journal ArticleDOI
Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus.
Luciene Covolan,Luiz E. Mello +1 more
TL;DR: Systemic administration of pilocarpine and kainic acid has been extensively used to model temporal lobe epilepsy in rats and differences in the temporal profile of cell damage should be taken into account when searching for neuroprotective agents are suggested.
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Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus.
TL;DR: Dentate granule cells were highly vulnerable to pilocarpine induced‐status epilepticus (SE), but were hardly damaged by kainate‐induced SE, and it is suggested that mossy‐fiber sprouting and neurogenesis of granules cells are not necessarily linked to one another.
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Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor.
Clement Hamani,Clement Hamani,Clement Hamani,Danilo C. Machado,Débora Cristina Hipólide,Francisco Paulino Dubiela,Deborah Suchecki,Carlos Eduardo Macedo,Fabio Tescarollo,Uilton Martins,Luciene Covolan,José N. Nobrega +11 more
TL;DR: The results suggest that the integrity of the serotonergic system is important for the anti-anhedonic-like effects of DBS but question a direct role of hippocampal BDNF.
Journal ArticleDOI
Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus
TL;DR: Dentate granule cells were highly vulnerable to pilocarpine induced-status epilepticus (SE), but were hardly damaged by kainate-induced SE, and it is suggested that mossy-fiber sprouting and neurogenesis of granules cells are not necessarily linked to one another.
Journal ArticleDOI
Deep brain stimulation in rats: Different targets induce similar antidepressant-like effects but influence different circuits
Clement Hamani,Clement Hamani,Beatriz Amorim,Anne L. Wheeler,Mustansir Diwan,Klaus Driesslein,Luciene Covolan,Christopher R. Butson,José N. Nobrega +8 more
TL;DR: Results from this study suggest that, despite similar antidepressant-like effects, stimulation of the vmPFC, WMF and Acb induces distinct changes in regional brain activity and functional connectivity.