L
Lucy Martine
Researcher at University of Burgundy
Publications - 43
Citations - 902
Lucy Martine is an academic researcher from University of Burgundy. The author has contributed to research in topics: Docosahexaenoic acid & Polyunsaturated fatty acid. The author has an hindex of 15, co-authored 36 publications receiving 789 citations. Previous affiliations of Lucy Martine include Centre national de la recherche scientifique & Institut national de la recherche agronomique.
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Journal ArticleDOI
Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina.
Lionel Bretillon,Ulf Diczfalusy,Ingemar Björkhem,Marie Annick Maire,Lucy Martine,Corinne Joffre,Niyazi Acar,Alain M. Bron,Catherine Creuzot-Garcher +8 more
TL;DR: The results of the current study are consistent with the primary hypothesis: the neural retina specifically expresses cholesterol-24S-hydroxylase, a metabolizing enzyme responsible for the removal of cholesterol in neurons.
Journal ArticleDOI
Oxyphytosterols are present in plasma of healthy human subjects.
André Grandgirard,Lucy Martine,Luc Demaison,Catherine Cordelet,Corinne Joffre,Olivier Berdeaux,Etienne Sémon +6 more
TL;DR: The oxidised derivatives of phytosterols (oxyphytosterols) were identified in plasma samples from thirteen healthy human volunteers, using MS to suggest that further research is necessary in this field.
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Gas chromatographic separation and mass spectrometric identification of mixtures of oxyphytosterol and oxycholesterol derivatives: Application to a phytosterol-enriched food
TL;DR: Pure individual phytosterols were prepared using reversed-phase HPLC in order to obtain the oxidized compounds of sitosterol, campesterol, stigmasterol and brassicasterol, and the gas chromatographic properties as well as the electronic impact mass spectra of these compounds were studied.
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Identification and quantification of phosphatidylcholines containing very-long-chain polyunsaturated fatty acid in bovine and human retina using liquid chromatography/tandem mass spectrometry.
TL;DR: This new HPLC-ESI-MS/MS method is sensitive and specific enough to structurally characterise and quantify all molecular PC species, including those esterified with VLC-PUFA, and may be useful for a better understanding of the pathogenesis of STD3.
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Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.
Corinne Joffre,Laurent Leclere,Bénédicte Buteau,Lucy Martine,Stéphanie Cabaret,L. Malvitte,Niyazi Acar,Gérard Lizard,Alain M. Bron,Catherine Creuzot-Garcher,Lionel Bretillon +10 more
TL;DR: The effects of three oxysterols on mitochondrial dysfunctions, inflammation, and oxidative stress in primary cultures of porcine retinal pigment epithelial (RPE) cells are investigated, concluding that in confluent primary porcines RPE cells, 24-hydroxycholesterol, 25-Hydroxych cholesterol, and 7-ketocholesterol are potent inducers of oxidation and inflammation.