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Luis A. López-Fernández

Researcher at Hospital General Universitario Gregorio Marañón

Publications -  83
Citations -  2237

Luis A. López-Fernández is an academic researcher from Hospital General Universitario Gregorio Marañón. The author has contributed to research in topics: Gene & Gene expression. The author has an hindex of 24, co-authored 79 publications receiving 2002 citations. Previous affiliations of Luis A. López-Fernández include University of Nice Sophia Antipolis & French Institute of Health and Medical Research.

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Journal ArticleDOI

DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis.

Miguel Garcia-Diaz, +11 more
- 25 Aug 2000 - 
TL;DR: Northern blotting, in situ hybridizationanalysis and immunostaining showed high levels of Pol l specifically expressed in testis, being developmentally regulated and mainly associ-ated to pachytene spermatocytes, suggesting a potential role ofPol l in DNA repair synthesis associated withmeiosis.
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Molecular Characterization of Spontaneous Mesenchymal Stem Cell Transformation

Daniel Rubio, +7 more
- 02 Jan 2008 - 
TL;DR: A two-stage model by which a human MSC becomes a tumor cell is proposed and it is proposed that MSC bypass senescence by upregulating c-myc and repressing p16 levels.
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Cellular Gene Expression Survey of Vaccinia Virus Infection of Human HeLa Cells

Susana Guerra, +5 more
- 01 Jun 2003 - 
TL;DR: This study is the first quantitative analysis of host gene expression following VV infection of cultured human cells, demonstrating global changes in the expression profile, and identifies upregulated genes with potential roles in the virus replication cycle.
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Distinct Gene Expression Profiling after Infection of Immature Human Monocyte-Derived Dendritic Cells by the Attenuated Poxvirus Vectors MVA and NYVAC

Susana Guerra, +7 more
- 15 Aug 2007 - 
TL;DR: Following MVA or NYVAC infection in MDDC, similarities as well as differences are found between these virus strains in the expression of cellular genes with immunological function, which should have an impact when these vectors are used as recombinant vaccines.
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Microarray analysis reveals characteristic changes of host cell gene expression in response to attenuated modified vaccinia virus Ankara infection of human HeLa cells.

Susana Guerra, +5 more
- 01 Jun 2004 - 
TL;DR: It is demonstrated that MVA infection triggered the induction of groups of genes, some of which may be involved in host resistance and immune modulation during virus infection, that were maintained during the course of infection.