Luisa Mosti

TL;DR: In this article, open-chain and cyclic sym-1,3-diones with N,N-dimethylformamide dimethyl acetal gave, generally in high yield, a series of sym-2-dimethylaminomethylene-1.3-Diones which reacted with phenylhydrazine and methylhydrazines to afford, generally, in satisfactory yield, 1,5-disubstituted 4-acylpyrazoles.

TL;DR: In this article, a series of carbinols 3a-f was prepared starting from methanols 1a -f via oxidation with pyridinium chlorochromate to aldehydes 2a-F, followed by a Grignard reaction of the latter.

TL;DR: In this paper, a series of 3-and 5-substituted 1-phenyl-1H-pyrazole-4-carboxylic acids were converted by heating 5-benzyl 1-methyl-1-methyl 1H pyrazole in quantitative yield.

TL;DR: In this paper, the relative esters of 4-substituted 2-amino-, 2-methyl- or 2-phenyl-5-pyrimidine carboxylic acids were obtained in moderate yields by reaction of the above dinucleophiles with ethyl 2,2-diformylacetate.

TL;DR: Ranise et al. as mentioned in this paper described their structure-based ligand design, synthetic strategy, and structure−activity relationship (SAR) studies that led to the identification of thiocarbamates (TCs), a novel class of NRTIs, isosteres of phenethylthiazolylthiourea (PETT) derivatives.