Lukas Forer

TL;DR: In this paper, the authors examined potential pitfalls on the sequencing results based on two-person mtDNA mixtures and compared three DNA polymerases, six different variant callers in five mixtures between 50% and 0.5% variant allele frequencies generated with two different amplification protocols.

TL;DR: Higher plasma levels of binding antibodies and antibodies in a surrogate neutralization assay were associated with reduced risk of breakthrough infection and assessment of anti-spike IgG levels enhanced prediction of breakthrough infections and may be a suitable measurable correlate of protection in practice.

TL;DR: This study shows that a family risk score and PGS capture different information concerning individual stroke risk, as demonstrated in a population-based study.

TL;DR: Cloudflow is presented, a high-level framework to hide the implementation details of Hadoop and to provide a set of building blocks to create biomedical pipelines in a more intuitive way and it will be shown how the framework can be combined with theHadoop workflow system Cloudgene and the cloud orchestration platform CloudMan to provide Hadoops pipelines as a service to everyone.

TL;DR: In this article, up to 70% of the LPA concentrations are a major independent risk factor for coronary artery disease (CAD) and are mainly determined by variation in LPA.