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Lynn R. Fraser

Researcher at King's College London

Publications -  112
Citations -  6077

Lynn R. Fraser is an academic researcher from King's College London. The author has contributed to research in topics: Capacitation & Sperm. The author has an hindex of 46, co-authored 112 publications receiving 5837 citations. Previous affiliations of Lynn R. Fraser include University of London & St George's Hospital.

Papers
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Fertility and ageing.

TL;DR: The late 20th century trend to delay birth of the first child until the age at which female fecundity or reproductive capacity is lower has increased the incidence of age-related infertility and stimulated interest in the possible factors in the female and the male that may contribute to the decline in fecundities with age.
Journal Article

Multiple gestation pregnancy

TL;DR: Reducing the multiple gestation pregnancy reproductive treatment treatment cycles because of the perceived need rate should be a high priority for assisted reproductive to stimulate excess follicles and transfer excess embryos in treatment programmes, despite the pressure from some order to achieve reasonable pregnancy rates.
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Ca2+‐Regulating mechanisms that modulate bull sperm capacitation and acrosomal exocytosis as determined by chlortetracycline analysis

TL;DR: It is suggested that Ca2+ is required for functional changes in bull sperm, with aCa2+‐ATPase modulating intracellular Ca2 + during capacitation and calcium channels controlling the Ca2- influx required for acrosomal exocytosis.
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A glycolytic product is obligatory for initiation of the sperm acrosome reaction and whiplash motility required for fertilization in the mouse.

Lynn R. Fraser, +1 more
- 01 Jan 1981 - 
TL;DR: In this article, the substrate requirements for capacitation of mouse spermatozoa, initiation of the acrosome reaction and support of fertilization of mouse eggs in vitro were examined by assessing not only fertilization rates, but also the stages of egg activation and sperm head decondensation in fertilized eggs to monitor the temporal aspects of these processes.
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17β‐Estradiol and environmental estrogens significantly affect mammalian sperm function*

TL;DR: This study provides the first evidence that E(2) and environmental estrogens can significantly stimulate mammalian sperm capacitation, acrosome reactions and fertilizing ability, with the environmental estrogen being much more potent than E( 2).