M
M. Berrettini
Researcher at University of Perugia
Publications - 42
Citations - 3481
M. Berrettini is an academic researcher from University of Perugia. The author has contributed to research in topics: Factor VII & Platelet. The author has an hindex of 22, co-authored 42 publications receiving 3393 citations. Previous affiliations of M. Berrettini include Scripps Health & University of Ferrara.
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Journal ArticleDOI
Bleeding complications of oral anticoagulant treatment: An inception-cohort, prospective collaborative study (ISCOAT)
Gualtiero Palareti,Nicoletta Leali,Sergio Coccheri,Mario Poggi,Cesare Manotti,Armando D'Angelo,Vittorio Pengo,Nicoletta Erba,Marco Moia,N. Ciavarella,Gianluigi Devoto,M. Berrettini,Serena Musolesi +12 more
TL;DR: Caution is required in elderly patients and anticoagulation intensity should be closely monitored to reduce periods of overdosing and see fewer bleeding events than those recorded in other observational and experimental studies.
Journal ArticleDOI
A randomized clinical trial of high-intensity warfarin vs. conventional antithrombotic therapy for the prevention of recurrent thrombosis in patients with the antiphospholipid syndrome (WAPS).
Guido Finazzi,Roberto Marchioli,Vincenzo Brancaccio,Piercarla Schinco,Finn Wisløff,Jacek Musiał,F. Baudo,M. Berrettini,Sophie Testa,Armando D'Angelo,G. Tognoni,T Barbui +11 more
TL;DR: High‐intensity warfarin was not superior to standard treatment in preventing recurrent thrombosis in patients with APS and was associated with an increased rate of minor hemorrhagic complications.
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Natural history and risk factors for thrombosis in 360 patients with antiphospholipid antibodies: A four-year prospective study from the italian registry
Guido Finazzi,Vincenzo Brancaccio,Marco Moia,N. Ciavarella,M. Gabriella Mazzucconi,Piercarla Schinco,Marco Ruggeri,Enrico Pogliani,Gabriella Gamba,Edoardo Rossi,Francesco Baudo,Cesare Manotti,Armando D'Angelo,Gualtiero Palareti,Valerio De Stefano,M. Berrettini,Tiziano Barbui +16 more
TL;DR: The present study shows that previous thrombosis and ACA titer > 40 U are independent predictors of thromBosis; history of miscarriage or vascular disease is significantly associated with adverse pregnancy outcome; and hematological malignancies can develop during follow-up in patients with antiphospholipid antibodies.
Journal ArticleDOI
Thrombotic events during oral anticoagulant treatment: results of the inception cohort prospective collaborative ISCOAT study
Gualtiero Palareti,Cesare Manotti,Armando D'Angelo,Vittorio Pengo,Nicoletta Erba,Marco Moia,N. Ciavarella,Gianluigi Devoto,M. Berrettini,Nicoletta Leali,Mario Poggi,Cristina Legnani,Serena Musolesi,Sergio Coccheri +13 more
TL;DR: A greater risk should be expected during the first 90 days of treatment, when anticoagulation levels are <2.0 INR, in patients > 70 years and in those with cerebrovascular/peripheral arterial disease.
Journal ArticleDOI
Activated human protein C prevents thrombin-induced thromboembolism in mice. Evidence that activated protein c reduces intravascular fibrin accumulation through the inhibition of additional thrombin generation.
Paolo Gresele,Stefania Momi,M. Berrettini,Giuseppe G. Nenci,Hp Schwarz,Nicola Semeraro,Mario Colucci +6 more
TL;DR: Results suggest that APC protects from thrombin-induced thromboembolism by rendering the formed fibrin more susceptible to plasmin degradation rather than by reducingfibrin formation.