M
M. E. De Broe
Researcher at University of Antwerp
Publications - 203
Citations - 5997
M. E. De Broe is an academic researcher from University of Antwerp. The author has contributed to research in topics: Alkaline phosphatase & Kidney. The author has an hindex of 43, co-authored 203 publications receiving 5833 citations.
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Aminoglycoside-induced ototoxicity.
TL;DR: Among the different pharmacodynamic hypotheses on the action of AGs, binding of the drug to acidic glycosaminoglycans in the stria vascularis, and interference by the drug with phosphoinositide metabolism in the hair cells seem to be of major importance.
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Interpretation and clinical significance of alkaline phosphatase isoenzyme patterns
V O Van Hoof,M. E. De Broe +1 more
TL;DR: This work proposes an alternative nomenclature for the ALP isoenzymes and isoforms based on their structural characteristics: soluble, dimeric (Sol), anchor-bearing (Anch), and membrane-bound (Mem) liver, bone, intestinal, and placental A...
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Hypozincemia in depression
TL;DR: Serum zinc levels were significantly lower in major depressed subjects than in normal controls, whereas minor depressed subjects showed intermediate values, and there were significant negative correlations between serum zinc, and severity of depression and plasma neopterin concentrations.
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Low serum levels of alkaline phosphatase of bone origin: a good marker of adynamic bone disease in haemodialysis patients
Marie M. Couttenye,Patrick C. D'Haese,V O Van Hoof,E. Lemoniatou,William G. Goodman,Gert A. Verpooten,M. E. De Broe +6 more
TL;DR: It is suggested that bone alkaline phosphatase, the closer physiological link with osteoblast function and the lesser expense for its determination, is a useful tool in the noninvasive diagnosis of the adynamic type of bone disease in the individual patient.
Journal Article
Immunohistochemical localization of placental alkaline phosphatase, carcinoembryonic antigen, and cancer antigen 125 in normal and neoplastic human lung.
TL;DR: The localization of HPLAP, CEA, and CA 125 in apparently normal constituents of all pulmonary specimens is in disagreement with the concept that the expression of these substances in the lung is indicative of abnormal cellular activity.