Patrick C. D'Haese

TL;DR: LC is a poorly absorbed, well-tolerated, and efficient phosphate binder in dialysis patients, who show almost no evolution toward low bone turnover over one year (unlike CC-treated patients), nor do they experience any aluminum-like effects on bone.

TL;DR: It is asserted that successful studies generally use suitable statistical approaches for biomarker definition and confirm results in independent test sets and a brief set of practical and feasible recommendations are described for investigators to properly identify and qualify proteomic biomarkers, which could also be used as reporting requirements.

TL;DR: Recent advances in understanding of the calcification paradox are reviewed, including protein expression patterns governing both normal and ectopic mineralization, the conversion of vascular smooth muscle cells to bone-like cells, and the regulatory pathways involved in both bone and vessel mineralization.

TL;DR: Application of LMB in saline waters need a careful risk evaluation due to potential lanthanum release, and issues related to La accumulation, increase of suspended solids and drastic resources depletion still need to be explored, in particular for sediment dwelling organisms.

TL;DR: Serum zinc levels were significantly lower in major depressed subjects than in normal controls, whereas minor depressed subjects showed intermediate values, and there were significant negative correlations between serum zinc, and severity of depression and plasma neopterin concentrations.