Showing papers in "Journal of Affective Disorders in 1994"
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TL;DR: The treatment of bipolar illness could be enhanced by public health efforts to promote early diagnosis and treatment; ensuring adequate trials of mood-stabilizers for patients with frequent recurrences; further research on bipolar disorder with prominent anxiety symptoms; and improved access to mental health care.
853 citations
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TL;DR: A cohort difference in 12-month MDE is found, with older women much more likely than older men to have recurrent episodes, and this sex difference in recurrence plays an important part in the elevated 12- month prevalence of depression among women compared to men in the 45-54 age range.
449 citations
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TL;DR: In the patients with major depression, the authors found significantly lower values of heart's beat-to-beat intervals and of the high-frequency peak of spectral analysis than in the other groups, indicating decreased parasympathetic activity.
291 citations
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TL;DR: The results suggest that brain high energy phosphate metabolism may be impaired in BP II and that there may be pathophysiological differences between BP I and BP II.
211 citations
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TL;DR: Serum zinc levels were significantly lower in major depressed subjects than in normal controls, whereas minor depressed subjects showed intermediate values, and there were significant negative correlations between serum zinc, and severity of depression and plasma neopterin concentrations.
205 citations
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TL;DR: Temperament, as measured by the Tridimensional Personality Questionnaire, accounted for 35% of the variance in treatment outcome, compared with less than 5% predicted by clinical variables in patients suffering from a current major depressive episode.
200 citations
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TL;DR: The results suggest that unipolar depression is associated with an acute phase response, which is possibly caused by changes in cytokines and corticosteroid secretion in depressed patients.
181 citations
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TL;DR: The dietary technique of acute tryptophan depletion was used to suppress brain serotonin synthesis in 16 women with documented premenstrual syndrome and caused a significant aggravation of pre menstrual symptoms, particularly irritability.
167 citations
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TL;DR: The suicides in the bipolar patients followed up retrospectively were significantly younger at onset and death than the index and control groups, and suicide was uncommon where follow-up extended over 10 years.
159 citations
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TL;DR: Both family history and the proband's diagnosis contribute independently to predicting response to long-term lithium response, and there were no significant differences in the rates of other psychiatric disorders.
155 citations
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TL;DR: Severity of depression and high neuroticism scores were the best predictors of persistence of persistent depressive symptoms.
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TL;DR: Significantly improved neuropsychological function was seen in the melancholic patients in the evening, in line with diurnal improvement in mood; there was also a large increase in strength.
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TL;DR: The most dramatic result was the high score for psychotic women with CBROI on the factor cognitive disorganization/psychosis, which reported homicidal ideation more frequently.
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TL;DR: There was a non-significant trend for bipolar depression to convey a higher risk for completed suicide than unipolar depression.
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TL;DR: Data do not indicate that (hypo)mania can be dichotomized on the basis of dysphoria, andvantages and disadvantages of dimensional and categorical approaches to specifying mood in mania or hypomania are discussed.
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TL;DR: All measures of social anxiety and avoidance, depression and social functioning showed a statistically significant change from baseline to end point in the open trial of sertraline.
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TL;DR: Assessment of patients meeting DSM-III-R criteria for non-psychotic major depressive disorder found differences between the self and clinician rating (the delta-IDS) were significantly correlated with non-endogenous depressive subtype, higher levels of neuroticism and dysfunctional attitudes, and lower self-esteem.
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TL;DR: The data suggest that more suicides might be averted by decisively treating Depressed patients with ADs, including strict monitoring of dosage and compliance, than by not treating them to avoid AD overdoses.
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TL;DR: It is shown that a 8 week fluoxetine could be beneficial to society provided society values a year of human life above a threshold varying from French Francs 23.800 to FF8.600 and as these values are extremely low compared to those found in the literature, it is concluded that an apparently costly innovation such as fluxetine may induce short-term financial savings for society.
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TL;DR: Cognitive dysfunctions found in some melancholic depressives could not be state-dependent and seem to indicate that the cognitive disfunctions are not likely to be only mnesic.
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TL;DR: Mood variability measures rather than average daily mood improvement correlate with the response to sleep deprivation, and these observations do not support theories of chronobiological rhythm disturbances in depression.
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TL;DR: The present findings indicate that depressed mood within a section of the general child population may be more stable and less transient than previously thought.
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TL;DR: 24-hour excretion of urinary free cortisol in patients with social phobia and post-dexamethasone cortisol levels in 64 patients withsocial phobia are examined and there is no evidence of HPA-axis overactivity compared to normal controls, despite pathological levels of anxiety.
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TL;DR: It is suggested that patients suffering from atypical depression may respond more favourably to moclobemide than to fluoxetine treatment.
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TL;DR: It is suggested that antidepressant treatment induces weight gain by mechanisms that are largely independent of their action on mood.
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TL;DR: Free hormone levels of 17 beta-estradiol and progesterone were determined in plasma using ultrafiltration and no significant difference could be found between women with and without postpartum blues.
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TL;DR: There was no evidence of immune system activation in euthymic bipolar patients and normal volunteers and bipolar patients could not be differentiated by medication status or gender.
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TL;DR: The P300 component of the event-related potential (ERP) may provide one neurophysiological index of cognitive dysfunction in depression, and is thought to index the updating of neurocognitive models concerned with the prediction of future events.
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TL;DR: In this paper, 15 patients with major depression who were being treated with bilateral electroconvulsive treatment (ECT) were investigated before and 45 min after a single ECT using split-dose Single Photon Emission Tomography (SPET or SPECT) with 99mTc-Exametazime.
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TL;DR: Prevalence and impact of comorbidity in early onset major depressive disorder were studied in depressed adult outpatients whose onset of first major depressive episode occurred by age 18 and in contrast to frequency of episodes, severity and duration of an index episode of major depression were not influenced by comor bidity.