M. Ermelinda S. Eusébio

TL;DR: In this paper, the thermal behavior of pyrazinamide polymorphs was investigated using differential scanning calorimetry (DSC) and polarized light thermal microscopy, supported by powder X-ray diffraction and infrared spectroscopy.

TL;DR: A 1:1 co-crystal involving pyrazinamide, one of the first-line drugs recommended by the World Health Organization for tuberculosis treatment, and diflunisal, a nonsteroidal anti-inflammatory substance, has been synthesized for the first time as mentioned in this paper.

TL;DR: Infrared spectra of 1,4-BDO isolated in low-temperature argon and xenon matrixes show a good agreement with a population-weighted mean theoretical spectrum, and the spectral features of the conformers expected to be trapped in the matrixes were observed experimentally.

TL;DR: The present work explores the possibilities of the matrix isolation technique in the structural characterisation of highly flexible molecules by identifying five conformers of 1,2-butanediol using a combination of FTIR spectroscopy and extensive theoretical calculations of vibrational spectra.

TL;DR: The FT-IR spectra of two diastereomers of 2,3-butanediol, isolated in low-temperature argon and xenon matrixes were studied, allowing the identification of two different conformers for each compound, enabling the establishment of a very weak intramolecular hydrogen bond of the O...H-O type.