M
M. Glória Bonecini-Almeida
Researcher at Oswaldo Cruz Foundation
Publications - 1
Citations - 147
M. Glória Bonecini-Almeida is an academic researcher from Oswaldo Cruz Foundation. The author has contributed to research in topics: Transforming growth factor & Receptor. The author has an hindex of 1, co-authored 1 publications receiving 135 citations.
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Down-Modulation of Lung Immune Responses by Interleukin-10 and Transforming Growth Factor β (TGF-β) and Analysis of TGF-β Receptors I and II in Active Tuberculosis
M. Glória Bonecini-Almeida,John L. Ho,Neio Boechat,Richard C. Huard,Sadhana Chitale,Howard Doo,Jiayuan Geng,Lorena Rego,Luiz Claudio Oliveira Lazzarini,Luiz Claudio Oliveira Lazzarini,Afrânio Lineu Kritski,Warren D. Johnson,Timothy A. McCaffrey,José Roberto Lapa e Silva +13 more
TL;DR: The data suggest that the combined production of the immunosuppressants IL-10 and TGF-β, as well as coexpression of T GF-β RI and RII, may act to down-modulate host anti-Mycobacterium tuberculosis immunity and thereby allow uncontrolled bacterial replication and overt disease.