M
M. J. Peckham
Researcher at The Royal Marsden NHS Foundation Trust
Publications - 102
Citations - 6593
M. J. Peckham is an academic researcher from The Royal Marsden NHS Foundation Trust. The author has contributed to research in topics: Chemotherapy & Seminoma. The author has an hindex of 40, co-authored 102 publications receiving 6526 citations. Previous affiliations of M. J. Peckham include Children's of Alabama & Institute of Cancer Research.
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Journal ArticleDOI
Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additivity.
G. Gordon Steel,M. J. Peckham +1 more
TL;DR: There are serious conceptual problems in demonstrating greater-than-additive cell kill whenever dose-response curves are nonlinear, so an approach based on an "envelope of additivity" in an iso-effect plot is suggested.
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The radioresponsiveness of human tumours and the initial slope ofthe cell survival curve
TL;DR: The surviving fraction at 2 Gy is shown to give good discrimination between resistant and sensitive tumour types and the relationship between the initial slope of the cell survival curve and clinical radioresponsiveness is demonstrated.
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Histopathology in the prediction of relapse of patients with stage i testicular teratoma treated by orchidectomy alone
L. S. Freedman,M. C. Parkinson,W. G. Jones,R. T. D. Oliver,M. J. Peckham,G. Read,Edward S. Newlands,C. J. Williams +7 more
TL;DR: 259 patients with stage I non-seminomatous germ-cell testicular teratoma treated by orchidectomy alone and monitored at one often centres in the United Kingdom were followed for a median of 30 months, with a 2-year relapse-free rate of 74%, falling to 68% at 4 years.
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The treatment of metastatic germ-cell testicular tumours with bleomycin, etoposide and cis-platin (BEP)
M. J. Peckham,A. Barrett,K. H. Liew,Alan Horwich,Bridget A. Robinson,H J Dobbs,T. J. McElwain,W F Hendry +7 more
TL;DR: BEP is a well tolerated and effective first line treatment for patients with metastatic germ-cell tumours and all 7 patients with advanced seminoma are alive and disease-free.
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Combined management of malignant teratoma of the testis
TL;DR: Intensive chemotherapy with bleomycin and vinblastine was used as initial treatment in patients with advanced testicular teratoma and after relapse following lymph-node irradiation in patientsWith early-stage disease, all 28 men with early- stage disease are alive and disease-free.