Alan Horwich

TL;DR: RCC appears to be more common in patients with obesity, end-stage renal failure, acquired renal cystic disease and tuber-ous sclerosis, and severalautosomal dominant syndromes are described, each with a dis-tinct genetic basis and phenotype.

TL;DR: An easily applicable, clinically based, prognostic classification for GCT has been agreed on between all the major clinical trial groups who are presently active worldwide and should be used in clinical practice and in the design and reporting of clinical trials to aid international collaboration and understanding.

TL;DR: A genome-wide association study using blood DNA samples from 1,854 individuals with clinically detected prostate cancer diagnosed at ≤60 years or with a family history of disease, and 1,894 population-screened controls with a low prostate-specific antigen (PSA) concentration (<0.5 ng/ml) identified seven loci associated with prostate cancer on chromosomes 3, 6, 7, 10, 11, 19 and X.

TL;DR: Conformal techniques significantly lowered the risk of late radiation-induced proctitis after radiotherapy for prostate cancer, and are the basis for dose-escalation studies to improve local tumour control.