D
Dasja Pajkrt
Researcher at University of Amsterdam
Publications - 170
Citations - 5638
Dasja Pajkrt is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 33, co-authored 134 publications receiving 4575 citations. Previous affiliations of Dasja Pajkrt include Boston Children's Hospital & Schering-Plough.
Papers
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Journal ArticleDOI
Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia.
Dasja Pajkrt,J. E. Doran,F. Koster,P. G. Lerch,B. Arnet,T. van der Poll,J W ten Cate,S. J. H. Van Deventer +7 more
TL;DR: Results suggest that rHDL may inhibit LPS effects in humans in vivo not only by binding and neutralizing LPS but also by reducing CD14 expression on monocytes.
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Proinflammatory Effects of IL-10 During Human Endotoxemia
TL;DR: In this paper, a bolus i.v. injection of LPS (4 ng/kg) in combination with either placebo or recombinant human IL-10 was administered just before or 1 h after LPS.
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Frequent Detection of Respiratory Viruses without Symptoms: Toward Defining Clinically Relevant Cutoff Values
Rogier R. Jansen,Joanne Wieringa,Sylvie M. Koekkoek,Caroline E. Visser,Dasja Pajkrt,Richard Molenkamp,Menno D. de Jong,Janke Schinkel +7 more
TL;DR: Asymptomatic carriage of a respiratory virus occurs frequently in young children, and significant differences in the amount of virus present were observed between cases and controls, suggesting that defining cutoff levels should be feasible and represents the next necessary step for diagnosing viral respiratory infections using molecular tests.
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Human Parechovirus Infections in Dutch Children and the Association between Serotype and Disease Severity
Kimberley S. M. Benschop,Janke Schinkel,René Minnaar,Dasja Pajkrt,L. Spanjerberg,H. C. Kraakman,B. Berkhout,Hans L. Zaaijer,Marcel Beld,Katja C. Wolthers +9 more
TL;DR: HPeV infections in young children during the period of 2000-2005 are reported and show an association between HPeV3 infection and sepsis-like illness and central nervous system involvement in neonates.
Journal ArticleDOI
Human Parechoviruses as an Important Viral Cause of Sepsislike Illness and Meningitis in Young Children
Katja C. Wolthers,Kimberley S. M. Benschop,Janke Schinkel,Richard Molenkamp,Rosemarijn M. Bergevoet,Ingrid J B Spijkerman,H. Carlijn Kraakman,Dasja Pajkrt +7 more
TL;DR: HPeV can be considered to be the second cause of viral sepsis and meningitis in young children, and rapid identification of HPeV by PCR could contribute to shorter duration of both antibiotic use and hospital stay.