M.R. Ven Murthy

TL;DR: A review of recent concepts and methodological developments on the complex interactions and complementary interrelationships between oxidative stress, mitochondrial dysfunction, and various forms of neural degeneration and fractionation and isolation of substances with antioxidant properties from plant materials, which can be expected to be less toxic in any pharmacological intervention.

TL;DR: In the Ayurvedic system, the herbs used for medicinal purposes are classed as brain tonics or rejuvenators, and the best known and most scientifically investigated of these herbs, Ashwagandha will be discussed in detail in this review.

TL;DR: The results suggest that neither Trx2 nor TrxR2 gain of function modified the redox regulation of mitochondria-dependent apoptosis in these mammalian cells.

TL;DR: A missense mutation at residue 207 of the lipoprotein lipase gene that is the most common cause of lipop protein lipase deficiency in French Canadians is identified and can be easily detected by dot blot analysis, providing opportunity for definitive DNA diagnosis of the disorder and identification of heterozygous carriers.

TL;DR: By examining the 10 coding exons of the LPL gene in another French Canadian patient, a third missense mutation is identified that causes a catalytically defective LPL protein and will allow for rapid screening in patients with LPL deficiency.