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M. van Glabbeke

Researcher at European Organisation for Research and Treatment of Cancer

Publications -  140
Citations -  12023

M. van Glabbeke is an academic researcher from European Organisation for Research and Treatment of Cancer. The author has contributed to research in topics: Soft tissue sarcoma & Chemotherapy. The author has an hindex of 50, co-authored 140 publications receiving 11261 citations.

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Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups.

TL;DR: The concomitant use of radiotherapy and chemotherapy resulted in a significantly improved locoregional control rate and a reduction of the need for colostomy in patients with locally advanced anal cancer without a significant increase in late side effects.
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Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma: final analysis of a randomized trial of the EORTC cooperative group of radiotherapy.

TL;DR: EORTC protocol 22791 compared once daily fractionation (CF) to pure hyperfractionation (HF) of 80.5 Gy in 70 fractions in 7 weeks using 2 fractions of 1.15 Gy per day in T2-T3 oropharyngeal carcinoma (excluding base of tongue), N0,N1 of less than 3 cm.
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Prognostic factors for the outcome of chemotherapy in advanced soft tissue sarcoma: an analysis of 2,185 patients treated with anthracycline-containing first-line regimens--a European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Study.

TL;DR: It is demonstrated that for advanced soft tissue sarcoma, response to chemotherapy is not predicted by the same factors as is overall survival time and needs to be taken into account in the interpretation of trials assessing the value of new agents for this disease on the basis of response to treatment.