M
M.W. Büchler
Researcher at Heidelberg University
Publications - 703
Citations - 28418
M.W. Büchler is an academic researcher from Heidelberg University. The author has contributed to research in topics: Pancreatitis & Pancreatic cancer. The author has an hindex of 67, co-authored 696 publications receiving 25796 citations. Previous affiliations of M.W. Büchler include University Hospital Heidelberg & University of Bern.
Papers
More filters
Journal ArticleDOI
DISPACT trial: a randomized controlled trial to compare two different surgical techniques of DIStal PAnCreaTectomy - study rationale and design.
Markus K. Diener,Hanns-Peter Knaebel,ST Witte,Inga Rossion,Meinhard Kieser,M.W. Büchler,Christoph M. Seiler +6 more
TL;DR: To evaluate the effectiveness of the two most common surgical techniques for distal pancreatectomy: stapler versus hand-sewn closure of the pancreatic remnant, a multicentered, randomized, controlled and patient-and observer-blinded trial using a two-group parallel group-sequential superiority design.
Journal ArticleDOI
Effector T lymphocyte subsets in human pancreatic cancer: detection of CD8+ CD18+ cells and CD8+ CD103+ cells by multi‐epitope imaging
K. Ademmer,Matthias P. Ebert,F. Müller-Ostermeyer,Helmut Friess,M.W. Büchler,Walter Schubert,P Malfertheiner +6 more
TL;DR: Pancreatic cancer cells develop several strategies to escape the T cell‐induced cytolysis by (i) the aggregation of cytotoxic CD8+ CD103+ T cells in the fibrous tissue distant from the tumour cells, and (ii) the presence of CD18‐bearing cells which lack the expression of the activation marker CD45RO.
Journal ArticleDOI
The microenvironment in chronic pancreatitis and pancreatic cancer induces neuronal plasticity
Ihsan Ekin Demir,G.O. Ceyhan,Ulrich Rauch,Burak Altintas,Markus Klotz,Michael W. Müller,M.W. Büchler,Helmut Friess,Karl-Herbert Schäfer +8 more
TL;DR: An in‐vitro simulation of the intrapancreatic neuroplasticity of the pancreas is achieved to better understand the mechanism of neuropathic alterations in chronic pancreatitis and pancreatic cancer.
Journal ArticleDOI
An audit of outcomes of a series of periampullary carcinomas
Pascal O. Berberat,Beat M. Künzli,Antanas Gulbinas,T. Ramanauskas,Jörg Kleeff,Martina Müller,Markus Wagner,Helmut Friess,M.W. Büchler +8 more
TL;DR: Only T1/T2 ampullary carcinomas have a good prognosis, whereas T3/T4 Ampullary tumors show aggressiveness similar to that of pancreatic head adenocarcinomas.