Maan-Gee Lee

TL;DR: Identified orexin neurons discharge during active waking, decrease discharge during quiet waking in absence of movement, and virtually cease firing during sleep, when postural muscle tone is low or absent; they increase firing before the end of PS and thereby herald the return of waking and muscle tone.

TL;DR: Findings indicate that the integrity of the septohippocampal GABAergic projection is sufficient to maintain some hippocampal theta activity, and hypothesize that cholinergic neurons serve to increase the population phase-locking of septal cells and thereby regulate the magnitude of hippocampalTheta.

TL;DR: It is shown for the first time that cholinergic neurons discharge in bursts at maximal rates during active waking and paradoxical sleep, when gamma and theta electroencephalographic activity are maximal.

TL;DR: Neurons containing melanin-concentrating hormone (MCH) are codistributed with neurons containing orexin (Orx or hypocretin) in the lateral hypothalamus, a peptide and region known to be critical for maintaining wakefulness, and could play a complementary role to Orx neurons in sleep–wake state regulation and contribute to the pathophysiology of certain sleep disorders.

TL;DR: The pharmacological actions of these flavonoids suggest their potential activity for treatment of allergic inflammatory diseases through the down-regulation of mast cell activation.