M
Maddalena Peghin
Researcher at Misericordia University
Publications - 22
Citations - 1008
Maddalena Peghin is an academic researcher from Misericordia University. The author has contributed to research in topics: Retrospective cohort study & Mortality rate. The author has an hindex of 14, co-authored 22 publications receiving 691 citations.
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Journal ArticleDOI
Treatment of Infections Due to MDR Gram-Negative Bacteria.
TL;DR: Treatment of severe MDR-GNB infections in critically ill patients in the near future will require an expert and complex clinical reasoning, of course taking into account the peculiar characteristics of the target population, but also the need for adequate empirical coverage and the more and more specific enzyme-level activity of novel antimicrobials with respect to the different resistance mechanisms.
Journal ArticleDOI
Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: Results from a single Italian Centre study on tocilizumab versus standard of care.
Luca Quartuccio,Arianna Sonaglia,Dennis McGonagle,Martina Fabris,Maddalena Peghin,Davide Pecori,Amato De Monte,Tiziana Bove,Francesco Curcio,Flavio Bassi,Salvatore De Vita,Carlo Tascini +11 more
TL;DR: Higher inflammatory markers, more infections and worse outcomes characterized ventilated TOCI cases compared to ward based TOCi, which suggests that therapy time in anti-cytokine randomized trials will be key.
Journal ArticleDOI
The management of multidrug-resistant Enterobacteriaceae.
TL;DR: The challenges in the treatment of patients with infections because of MDR Enterobacteriaceae are discussed and an expert opinion is provided while awaiting for more definitive data.
Journal ArticleDOI
Risk stratification and treatment of ICU-acquired pneumonia caused by multidrug- resistant/extensively drug-resistant/pandrug-resistant bacteria
TL;DR: The exponential increase of antimicrobial resistance among virulent pathogens currently represents one of the main challenges for clinicians in the intensive care unit.
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Patient specific risk stratification for antimicrobial resistance and possible treatment strategies in gram-negative bacterial infections
TL;DR: This article covers MDRGN epidemiology, with a specific focus on risk factors for harbouring infections sustained by extended-spectrum-Beta-lactamase (ESBL), carbapenem resistant Enterobacteriacae (CRE), MDR Pseudomonas aeruginosa and MDR Acinetobacter baumanii, and proposes an algorithm for the choice of empiric treatment when a MDR GN infection is suspected.