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Arianna Sonaglia

Researcher at University of Udine

Publications -  13
Citations -  289

Arianna Sonaglia is an academic researcher from University of Udine. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 4, co-authored 5 publications receiving 190 citations.

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Journal ArticleDOI

Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: Results from a single Italian Centre study on tocilizumab versus standard of care.

TL;DR: Higher inflammatory markers, more infections and worse outcomes characterized ventilated TOCI cases compared to ward based TOCi, which suggests that therapy time in anti-cytokine randomized trials will be key.
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Higher levels of IL-6 early after tocilizumab distinguish survivors from nonsurvivors in COVID-19 pneumonia: A possible indication for deeper targeting of IL-6.

TL;DR: The most serious COVID‐19 deriving from severe acute respiratory syndrome coronavirus 2 causes a cytokine release storm and it is associated with worse outcomes, and blocking IL‐6 preliminarily resulted in the improvement of this hyperinflammatory state.
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Interleukin 6, soluble interleukin 2 receptor alpha (CD25), monocyte colony-stimulating factor, and hepatocyte growth factor linked with systemic hyperinflammation, innate immunity hyperactivation, and organ damage in COVID-19 pneumonia.

TL;DR: IL-6, M-CSF, sIL-2Rα, and HGF are possibly involved in the main biological processes of severe COVID-19, mirroring the level of systemic hyperinflammatory state, thelevel of lung inflammation, and the severity of organ damage.
Posted ContentDOI

Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care.

TL;DR: Higher inflammatory markers, more superimposed infections and worse outcomes characterized ventilated TOCI cases compared to ward based TOCi therapy, and this study suggests that therapy time in anti-cytokine randomized clinical trials will be key.
Journal ArticleDOI

Post-COVID-19 Arthritis and Sacroiliitis: Natural History with Longitudinal Magnetic Resonance Imaging Study in Two Cases and Review of the Literature.

TL;DR: In this paper, the authors report the natural history of sacroiliac inflammatory involvement in two females who developed COVID-19 infection with mild flu-like symptoms after the infection.