Madeline Polak

TL;DR: A 3-month internet-mediated, pedometer-based PA intervention was associated with reduced risk for AEs of COPD over 12-15 months of follow-up and there were no significant between-group differences in change in average daily step count, HRQL, or self-efficacy.

TL;DR: In this paper, the authors evaluated the effectiveness of a web-based self-management intervention, focused on physical activity promotion, on exercise capacity in COPD, and found that participants were significantly more engaged with the intervention, although site did not modify the effect of the intervention on 6MWD or secondary outcomes.

TL;DR: Letrozole/abemaciclib demonstrated encouraging and durable evidence of activity in recurrent ER positive endometrioid EC, and exploratory tumor profiling revealed several mechanistically relevant candidate predictors of response or absence of response (CTNNB1, KRAS, and CDKN2A mutations), which require independent validation.

TL;DR: It is suggested that treatment with avelumab and talazoparib has a favorable toxic effects profile and support further investigation in certain subsets of patients with recurrent MMRP EC.

TL;DR: Plasma 25(OH)D level in chronic SCI is not associated with clinical factors specific to SCI such as injury level and completeness, injury duration, and mobility mode, but related to supplement intake and other lifestyle factors.