Magali Verheecke

TL;DR: Prenatal exposure to maternal cancer with or without treatment did not impair the cognitive, cardiac, or general development of children in early childhood andPrematurity was correlated with a worse cognitive outcome, but this effect was independent of cancer treatment.

TL;DR: The data indicate that babies exposed to antenatal chemotherapy might be more likely to develop complications, specifically small for gestational age and NICU admission, than babies not exposed, and recommend involving hospitals with obstetric high-care units in the management of these patients.

TL;DR: It is shown that plasma DNA profiling allows for presymptomatic detection of tumors in pregnant women undergoing routine NIPT and that maternal plasma cell-free DNA sequencing for noninvasive prenatal testing also may enable accurate presympton detection of maternal tumors and treatment during pregnancy.

TL;DR: In early and advanced stage nodular sclerosis Hodgkin's lymphoma, genomic imbalances in Hodgkin/Reed-Sternberg cells can be identified by massive parallel sequencing of circulating cell-free DNA at diagnosis.

TL;DR: The observation that chemotherapy administered during the second or third trimester of pregnancy, that is, after the period of organogenesis, has little effect on the long-term outcome of children adds to the therapeutic armamentarium during pregnancy.