M
Magnolia Bostick
Researcher at University of California, Los Angeles
Publications - 15
Citations - 3599
Magnolia Bostick is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: DNA methylation & Cullin. The author has an hindex of 9, co-authored 15 publications receiving 3170 citations. Previous affiliations of Magnolia Bostick include University of California, Davis.
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Journal ArticleDOI
UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells
Magnolia Bostick,Jong Kyong Kim,Pierre-Olivier Estève,Amander T. Clark,Sriharsa Pradhan,Steven E. Jacobsen +5 more
TL;DR: The data suggest that UHRF1 may help recruit DNMT1 to hemimethylated DNA to facilitate faithful maintenance of DNA methylation.
Journal ArticleDOI
Conservation and divergence of methylation patterning in plants and animals
Suhua Feng,Shawn J. Cokus,Xiaoyu Zhang,Pao-Yang Chen,Magnolia Bostick,Mary G. Goll,Jonathan Hetzel,Jayati Jain,Steven H. Strauss,Marnie E. Halpern,Chinweike Ukomadu,Kirsten C. Sadler,Sriharsa Pradhan,Matteo Pellegrini,Steven E. Jacobsen +14 more
TL;DR: Comparisons of DNA methylation in eight diverse plant and animal genomes found that patterns of methylation are very similar in flowering plants with methylated cytosines detected in all sequence contexts, whereas CG methylation predominates in animals.
Journal ArticleDOI
The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Hideharu Hashimoto,John R. Horton,Xing Zhang,Magnolia Bostick,Steven E. Jacobsen,Xiaodong Cheng +5 more
TL;DR: UHRF1 contains a previously unknown DNA-binding module and is the first example of a non-enzymatic, sequence-specific DNA- binding protein domain to use the base flipping mechanism to interact with DNA.
Journal ArticleDOI
The SRA Methyl-Cytosine-Binding Domain Links DNA and Histone Methylation
Lianna M. Johnson,Magnolia Bostick,Xiaoyu Zhang,Edward Kraft,Ian R. Henderson,Judy Callis,Steven E. Jacobsen +6 more
TL;DR: It is shown that KYP-dependent H3K9me2 is found at non-CG methylation sites in addition to those rich in CG methylation, and the SRA domains from KYP and SRA-RING proteins prefer methylcytosines in different sequence contexts, suggesting a self-reinforcing loop between histone and DNA methylation.
Journal ArticleDOI
Arabidopsis Has Two Redundant Cullin3 Proteins That Are Essential for Embryo Development and That Interact with RBX1 and BTB Proteins to Form Multisubunit E3 Ubiquitin Ligase Complexes in Vivo
Pablo Figueroa,Giuliana Gusmaroli,Giovanna Serino,Jessica Habashi,Ligeng Ma,Ligeng Ma,Yunping Shen,Yunping Shen,Suhua Feng,Magnolia Bostick,Judy Callis,Hanjo Hellmann,Xing Wang Deng +12 more
TL;DR: It is demonstrated that Arabidopsis thaliana has two redundant CUL3 (AtCUL3) genes that are essential for embryo development and cofractionates and specifically associates with AtRBX1 and a representative BTB protein in vivo.