M
Mahendra D. Chordia
Researcher at University of Virginia
Publications - 103
Citations - 1881
Mahendra D. Chordia is an academic researcher from University of Virginia. The author has contributed to research in topics: Medicine & Paclitaxel. The author has an hindex of 25, co-authored 92 publications receiving 1648 citations. Previous affiliations of Mahendra D. Chordia include University of Virginia Health System & National Chemical Laboratory.
Papers
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Journal ArticleDOI
Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server
Heping Zheng,Mahendra D. Chordia,David R. Cooper,Maksymilian Chruszcz,Maksymilian Chruszcz,Peter Müller,George M. Sheldrick,Wladek Minor +7 more
TL;DR: The protocol outlines how the CMM server can be used to detect geometric and other irregularities in the structures of metal-binding sites, as well as how it can alert researchers to potential errors in metal assignment.
Journal ArticleDOI
Unexpectedly Facile Hydrolysis of the 2-Benzoate Group of Taxol and Syntheses of Analogs with Increased Activities
Ashok G. Chaudhary,Milind M. Gharpure,John M. Rimoldi,Mahendra D. Chordia,David G. I. Kingston,Surinder Grover,Chii M. Lin,Ernest Hamel,A. A. Leslie Gunatilaka +8 more
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A Novel Neutrophil-Specific PET Imaging Agent: cFLFLFK-PEG-64Cu
Landon W. Locke,Mahendra D. Chordia,Yi Zhang,Bijoy Kundu,Dylan P. Kennedy,Jessica Landseadel,Li Xiao,Karen D. Fairchild,Stuart S. Berr,Joel Linden,Dongfeng Pan +10 more
TL;DR: In this paper, the synthesis and validation of a new, highly potent 64Cu-labeled peptide, cFLFLFK-PEG-64Cu, that targets the formyl peptide receptor (FPR) on leukocytes is described.
A Novel Neutrophil-Specific PET Imaging Agent: cFLFLFK-PEG- 64 Cu
Landon W. Locke,Mahendra D. Chordia,Yi Zhang,Bijoy Kundu,Dylan P. Kennedy,Jessica Landseadel,Li Xiao,Karen D. Fairchild,Stuart S. Berr,Joel M. Linden,Dongfeng Pan +10 more
TL;DR: This new radiolabeled peptide targeting the FPR binds to neutrophils in vitro and accumulates at sites of inflammation in vivo and may prove to be a useful tool to probe inflammation or injury.
Journal ArticleDOI
In vitro metabolism of 2-acetylbenzothiophene: relevance to zileuton hepatotoxicity.
TL;DR: In vitro and in vivo data presented here demonstrate the formation of 2-ABT from zileuton and its further bioactivation to a potentially toxic metabolite.