M
Maksymilian Chruszcz
Researcher at University of South Carolina
Publications - 168
Citations - 7719
Maksymilian Chruszcz is an academic researcher from University of South Carolina. The author has contributed to research in topics: Crystal structure & Epitope. The author has an hindex of 36, co-authored 149 publications receiving 6573 citations. Previous affiliations of Maksymilian Chruszcz include Polish Academy of Sciences & University of Virginia.
Papers
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HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes.
TL;DR: A new approach that integrates data collection, data reduction, phasing and model building significantly accelerates the process of structure determination and on average minimizes the number of data sets and synchrotron time required for structure solution.
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Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
Karolina A. Majorek,Przemyslaw J. Porebski,Arjun Dayal,Matthew D. Zimmerman,Kamila Jablonska,Alan J. Stewart,Maksymilian Chruszcz,Wladek Minor +7 more
TL;DR: In this paper, the crystal structures of albumins from cattle (BSA), horse (ESA) and rabbit (RSA) sera were analyzed in the context of their potential allergenicity and cross-reactivity.
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Double chromodomains cooperate to recognize the methylated histone H3 tail
John F. Flanagan,Li-Zhi Mi,Maksymilian Chruszcz,Marcin Cymborowski,Katrina L. Clines,Youngchang Kim,Wladek Minor,Fraydoon Rastinejad,Sepideh Khorasanizadeh +8 more
TL;DR: It is shown that the human CHD1 double chromodomains target the lysine 4-methylated histone H3 tail (H3K4me), a hallmark of active chromatin, and its interactions with histone tails.
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Phosphorylation regulates SIRT1 function.
Tsutomu Sasaki,Bernhard Maier,K.D. Koclega,Maksymilian Chruszcz,Wendy Gluba,P. Todd Stukenberg,Wladek Minor,Heidi Scrable +7 more
TL;DR: In this article, the authors identified 13 residues in SIRT1 that are phosphorylated in vivo using mass spectrometry and found that phosphorylation by phosphatases in vitro resulted in decreased NAD+-dependent deacetylase activity.
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Data Mining of Metal Ion Environments Present in Protein Structures
TL;DR: By measuring the frequency of each amino acid in metal ion-binding sites, the positive or negative preferences of each residue for each type of cation were identified and may be used for fast identification of metal-binding structural motifs that cannot be identified on the basis of sequence similarity alone.