M
Maia Uriarte
Researcher at National University of La Plata
Publications - 9
Citations - 256
Maia Uriarte is an academic researcher from National University of La Plata. The author has contributed to research in topics: Ghrelin & Growth hormone secretagogue receptor. The author has an hindex of 5, co-authored 7 publications receiving 165 citations. Previous affiliations of Maia Uriarte include Louisiana State University.
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Journal ArticleDOI
Insulin‐like growth factor‐i gene therapy increases hippocampal neurogenesis, astrocyte branching and improves spatial memory in female aging rats
Joaquín Pardo,Maia Uriarte,Gloria M. Cónsole,Paula C. Reggiani,Tiago F. Outeiro,Gustavo R. Morel,Rodolfo G. Goya +6 more
TL;DR: It is concluded that the ependymal route is an effective approach to increase CSF levels of IGF‐I and that this strategy improves the accuracy of spatial memory in aging rats.
Journal ArticleDOI
Brain accessibility delineates the central effects of circulating ghrelin
Mario Perello,Agustina Cabral,María Paula Cornejo,Pablo Nicolás de Francesco,Gimena Fernandez,Maia Uriarte +5 more
TL;DR: Some potential features regarding the accessibility of plasma ghrelin into the human brain based on the observations reported by studies that investigate the consequences of gh Relin administration to humans are discussed.
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Evidence Supporting a Role for the Blood-Cerebrospinal Fluid Barrier Transporting Circulating Ghrelin into the Brain.
Maia Uriarte,Pablo Nicolás de Francesco,Gimena Fernandez,Agustina Cabral,Daniel Castrogiovanni,Tyler Lalonde,Leonard G. Luyt,Sebastián A. Trejo,Mario Perello +8 more
TL;DR: Current evidence suggests that the blood-CSF barrier can transport circulating ghrelin into the brain, and that the access of ghrel in into the CSF is required for its full orexigenic effect.
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Circulating Ghrelin Acts on GABA Neurons of the Area Postrema and Mediates Gastric Emptying in Male Mice
Agustina Cabral,María Paula Cornejo,Gimena Fernandez,Pablo Nicolás de Francesco,Guadalupe Garcia-Romero,Maia Uriarte,Jeffrey M. Zigman,Enrique Leo Portiansky,Mirta Reynaldo,Mario Perello +9 more
TL;DR: It is shown that the capacity of circulating ghrelin to acutely induce gastric emptying in mice requires the integrity of the AP, which contains a population of GABA neurons that are a target of plasma ghrelIn.
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Therapeutic potential of IGF-I on hippocampal neurogenesis and function during aging
TL;DR: IGF-I emerges as a promising restorative molecule for increasing hippocampal neurogenesis and memory accuracy in aged individuals and possibly, in neurodegenerative pathologies.