Mandy L. Ford

TL;DR: To further characterize glycan‐based species incompatibilities, human and non‐human primate antibody binding to cells derived from genetically modified pigs lacking these carbohydrate‐modifying genes was examined.

TL;DR: Recommendations on the definition and utilization of HLA diagnostic testing, and a framework for clinical assessment of risk for a memory or a primary alloimmune response are provided, intended to spur research that will inform the next STAR Working Group meeting in 2019.

TL;DR: This description of the longest reported survival of pig‐to‐non‐human primate kidney xenotransplantation, now >125 days, provides promise for further study and potential clinical translation.

TL;DR: In this paper, the authors proposed a pig-to-non-human primate kidney xenotransplantation (P2P-XenOTransplant) model, where the anti-pig antibodies are an important component of the xenogeneic immune response.

TL;DR: Results indicate that two disparate, clinically relevant models of sepsis induce a significant increase in intestinal permeability mediated through a common pathway involving alterations inClaudin 2, claudin 5, JAM-A, and occludin although model-specific differences in ZO-1 were also identified.